Evidence map›Paper›PMID 38596483›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)

The AUstralian multidomain Approach to Reduce dementia Risk by prOtecting brain health With lifestyle intervention study (AU-ARROW): A study protocol for a single-blind, multi-site, randomized controlled trial.

Samantha L Gardener, Stephanie J Fuller, Sharon L Naismith, Laura Baker, Miia Kivipelto, Victor L Villemagne, Stuart M Grieve, Paul Yates, Stephanie R Rainey-Smith, Juliana Chen and 14 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 13 institutions in 3 countries.

Samantha L GardenerCentre of Excellence for Alzheimer's Disease Research and Care School of Medical and Health Sciences Edith Cowan University Joondalup Western Australia Australia.ORCID https://orcid.org/0000-0002-1933-5260
Stephanie J FullerDepartment of Biomedical Sciences Macquarie University Sydney New South Wales Australia.
Sharon L NaismithThe University of Sydney Sydney New South Wales Australia.
Laura BakerWake Forest University School of Medicine Winston-Salem North Carolina USA.
Miia KivipeltoKarolinska Institutet Solna Stockholm Sweden.
Victor L VillemagneCentre of Excellence for Alzheimer's Disease Research and Care School of Medical and Health Sciences Edith Cowan University Joondalup Western Australia Australia.
Stuart M GrieveImaging and Phenotyping Laboratory, Charles Perkins Centre, Faculty of Medicine and Health, University of Sydney Sydney New South Wales Australia.
Paul YatesAustin Health, Department of Nuclear Medicine and Centre for Positron Emission Tomography Heidelberg Victoria Australia.
Stephanie R Rainey-SmithCentre of Excellence for Alzheimer's Disease Research and Care School of Medical and Health Sciences Edith Cowan University Joondalup Western Australia Australia.
Juliana ChenDepartment of Biomedical Sciences Macquarie University Sydney New South Wales Australia.
Belinda ThompsonDepartment of Health Sciences Australian Lymphoedema Education Research and Treatment Macquarie University Sydney New South Wales Australia.
Nicola J ArmstrongCurtin University Bentley Western Australia Australia.
Malika G FernandoDepartment of Biomedical Sciences Macquarie University Sydney New South Wales Australia.
Carolina Blagojevic CastroAlzheimer's Research Australia Ralph and Patricia Sarich Neuroscience Research Institute Nedlands Western Australia Australia.
Silochna MeghwarDepartment of Biomedical Sciences Macquarie University Sydney New South Wales Australia.
Rema RamanAlzheimer's Therapeutic Research Institute University of Southern California San Diego California USA.
Andrew GleasonDepartment of Biomedical Sciences Macquarie University Sydney New South Wales Australia.
Catriona IrelandThe University of Sydney Sydney New South Wales Australia.
Roger ClarnetteThe University of Western Australia Perth Western Australia Australia.
Kaarin J AnsteyUniversity of New South Wales Sydney New South Wales Australia.
Kevin TaddeiCentre of Excellence for Alzheimer's Disease Research and Care School of Medical and Health Sciences Edith Cowan University Joondalup Western Australia Australia.
Manohar GargDepartment of Biomedical Sciences Macquarie University Sydney New South Wales Australia.
Hamid R SohrabiCentre of Excellence for Alzheimer's Disease Research and Care School of Medical and Health Sciences Edith Cowan University Joondalup Western Australia Australia.
Ralph N MartinsCentre of Excellence for Alzheimer's Disease Research and Care School of Medical and Health Sciences Edith Cowan University Joondalup Western Australia Australia.
Edith Cowan University · AUMacquarie University · AUThe University of Sydney · AUCurtin University · AUGovernment of Western Australia Department of Health · AUItron (United States) · USKarolinska Institutet · SEMurdoch University · AUThe University of Melbourne · AUThe University of Western Australia · AUUniversity of Southern California · USUNSW Sydney · AUWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Finnish Geriatric Intervention Study (FINGER) led to the global dementia risk reduction initiative: World-Wide FINGERS (WW-FINGERS). As part of WW-FINGERS, the Australian AU-ARROW study mirrors aspects of FINGER, as well as US-POINTER.

methodAU-ARROW is a randomized, single-blind, multisite, 2-year clinical trial ( DISCUSSION: The finalized AU-ARROW protocol is expected to allow development of an evidence-based innovative treatment plan to reduce cognitive decline and dementia risk, and effective transfer of research outcomes into Australian health policy. Highlights: Study protocol for a single-blind, randomized controlled trial, the AU-ARROW Study.The AU-ARROW Study is a member of the World-Wide FINGERS (WW-FINGERS) initiative.AU-ARROW's primary outcome measure is change in a global composite cognitive score.Extra significance from amyloid PET imaging, brain MRI, and retinal biomarker tests.Leading to development of an innovative treatment plan to reduce cognitive decline.

Indexed as

Alzheimer's diseaseAustraliabrain healthdementiamultidomain lifestyle interventionrandomized controlled trialstudy protocol

Identifiers

PMID38596483
PMCPMC11002765
OpenAlexW4394620114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.