Evidence map›Paper›PMID 38596426›Full record

ArticleThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2024

Evaluating the Impact of Eat, Sleep, Console in Neonatal Abstinence Syndrome Treatment for Infants Exposed to Substance Use

Shannon V McGrath, Allie Rivera, Christopher Kennie-Richardson, David Ehrmann, Julie Cline, Kaye Gable, Victoria Forrest

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Article in The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shannon V McGrathDepartment of Pharmacy (SVM, JC, CK-R, AR, VF), Cone Health Women's and Children's Center, Greensboro, NC.
Allie RiveraDepartment of Pharmacy (SVM, JC, CK-R, AR, VF), Cone Health Women's and Children's Center, Greensboro, NC.
Christopher Kennie-RichardsonDepartment of Pharmacy (SVM, JC, CK-R, AR, VF), Cone Health Women's and Children's Center, Greensboro, NC.
David EhrmannDepartment of Neonatology (DE, KG), Cone Health Women's and Children's Center, Greensboro, NC.
Julie ClineDepartment of Pharmacy (SVM, JC, CK-R, AR, VF), Cone Health Women's and Children's Center, Greensboro, NC.
Kaye GableDepartment of Neonatology (DE, KG), Cone Health Women's and Children's Center, Greensboro, NC.
Victoria ForrestDepartment of Pharmacy (SVM, JC, CK-R, AR, VF), Cone Health Women's and Children's Center, Greensboro, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAn increase in maternal use of licit or illicit substances, alcohol, and tobacco has resulted in an increased incidence of neonatal abstinence syndrome (NAS). In recent years, NAS management has shifted to initiating an Eat, Sleep, Console (ESC) approach prior to pharmacologic treatment. The objective of this study was to evaluate the impact of ESC in combination with pharmacologic treatment in the management of NAS for infants exposed to substance use

methodsThis single system, multisite, retrospective cohort study evaluated infants with known exposure to substance or polysubstance use

resultsA total of 2843 patients were screened, and 50 patients were randomly selected for -inclusion in both pre- and post-groups. The rate of pharmacologic therapy initiated post implementation of ESC decreased from 58% to 30% (p < 0.01). In the post-group, there was a decrease in the number of -patients requiring scheduled morphine (33%, p < 0.01) and duration of pharmacologic therapy (14.6 days vs 6.47 days, p < 0.01).

conclusionsImplementing an ESC guideline decreased the length of stay and rate of pharmacologic intervention needed for infants with NAS at our institution.

Indexed as

infantneonatal abstinence syndromepregnancy

Identifiers

PMID38596426
PMCPMC11001210

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.