Evidence map›Paper›PMID 38595924›Full record

ArticleFrontiers in pharmacology2024

Design and synthesis of novel dihydropyridine- and benzylideneimine-based tyrosinase inhibitors.

Ifraz Ahmad, Warda Parveen, Shah Noor, Zahoor Udin, Amjad Ali, Ijaz Ali, Riaz Ullah, Hamid Ali

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Ifraz Ahmad *Key Laboratory of Automobile Materials, Department of Material Sciences and Engineering, Jilin University, Changchun, China.
Warda Parveen *Key Laboratory of Automobile Materials, Department of Material Sciences and Engineering, Jilin University, Changchun, China.
Shah NoorKey Laboratory of Automobile Materials, Department of Material Sciences and Engineering, Jilin University, Changchun, China.
Zahoor UdinChemistry Department, Gomal University, Dera Ismail Khan, Pakistan.
Amjad AliFaculty of Biological Sciences, Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan.
Ijaz AliCentre for Applied Mathematics and Bioinformatics (CAMB), Gulf University for Science and Technology, Hawally, Kuwait.
Riaz UllahDepartment of Pharmacognosy, College of Pharmacy King Saud University, Riyadh, Saudi Arabia.
Hamid AliDepartment of Biosciences, COMSATS University Islamabad, Islamabad, Pakistan.
Jilin University · CNCOMSATS University Islamabad · PKGomal University · PKGulf University for Science & Technology · KWKing Saud University · SAQuaid-i-Azam University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tyrosinase (TYR) inhibitors are very significant as they inhibit enzyme tyrosinase activity, and its inhibition is vital for skin care, anticancer medication, and antibrowning of fruits and vegetables. This work presents a novel and economical route for the preparation of new synthetic tyrosinase inhibitors using amlodipine

Indexed as

amlodipineantibrowninganticancerbenzylideneiminedihydropyridineskin caretyrosinase inhibitorstyrosine kinase

Identifiers

PMID38595924
PMCPMC11002185
OpenAlexW4393197648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.