Evidence map›Paper›PMID 38595691›Full record

ArticleClinical neurophysiology practice2024

Examining short interval intracortical inhibition with different transcranial magnetic stimulation-induced current directions in ALS.

Roisin McMackin, Yasmine Tadjine, Antonio Fasano, Matthew Mitchell, Mark Heverin, Friedemann Awiszus, Bahman Nasseroleslami, Richard G Carson, Orla Hardiman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical neurophysiology practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. TMS-Based Neurofeedback Training of Mental Finger Individuation Induces Neuroplastic Changes in the Sensorimotor System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Roisin McMackinDiscipline of Physiology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Ireland.
Yasmine TadjineAcademic Unit of Neurology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Ireland.
Antonio FasanoAcademic Unit of Neurology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Ireland.
Matthew MitchellAcademic Unit of Neurology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Ireland.
Mark HeverinAcademic Unit of Neurology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Ireland.
Friedemann AwiszusDepartment of Orthopaedic Surgery, Otto-von-Guericke University, Magdeburg, Germany.
Bahman NasseroleslamiAcademic Unit of Neurology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Ireland.
Richard G CarsonTrinity College Institute of Neuroscience and School of Psychology, Trinity College Dublin, University of Dublin, Ireland.
Orla HardimanAcademic Unit of Neurology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Ireland.
Trinity College Dublin · IEOtto-von-Guericke-Universität Magdeburg · DEQueen's University Belfast · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To establish if induced current direction across the motor cortex alters the sensitivity of transcranial magnetic stimulation (TMS)-evoked short-interval intracortical inhibition (SICI) as an ALS biomarker. Methods: Threshold tracking-TMS was undertaken in 35 people with ALS and 39 controls. Using a coil orientation which induces posterior-anterior (PA)-directed current across the motor cortex, SICI (1 ms and 3 ms interstimulus intervals) and intracortical facilitation (ICF, 10 ms interstimulus interval) were recorded. SICI Results: At group level, SICI Conclusions: SICI Significance: Examining both SICI

Indexed as

Amyotrophic lateral sclerosisCoil orientationIntracortical facilitationShort-interval intracortical inhibitionThreshold trackingTranscranial magnetic stimulation

Identifiers

PMID38595691
PMCPMC11002888
OpenAlexW4392767902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.