Evidence map›Paper›PMID 38594507›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Does thyroglossal duct arborization play a role in the post-surgical outcome of Sistrunk procedure in children?

Claudio Spinelli, Marco Ghionzoli, Clara Ugolini, Chiara Oreglio, Carla Guglielmo, Antonino Morabito, Armando Patrizio, Poupak Fallahi, Silvia Martina Ferrari, Alessandro Antonelli

Open access · hybridAbstract read
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Claudio SpinelliDivision of Pediatric and Adolescent Surgery, Department of Surgery, University of Pisa, Pisa, Italy.
Marco GhionzoliDivision of Pediatric and Adolescent Surgery, Department of Surgery, University of Pisa, Pisa, Italy.
Clara UgoliniDepartment of Surgical, Medical, Molecular Pathology and Critical Area, University of Pisa, Pisa, Italia.
Chiara OreglioDepartment of Pediatric Surgery, Meyer Children's Hospital, University of Florence, Florence, Italy.
Carla GuglielmoDivision of Pediatric and Adolescent Surgery, Department of Surgery, University of Pisa, Pisa, Italy.
Antonino MorabitoDepartment of Pediatric Surgery, Meyer Children's Hospital, University of Florence, Florence, Italy.
Armando PatrizioDepartment of Emergency Medicine, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Poupak FallahiDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Silvia Martina FerrariDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Alessandro AntonelliDepartment of Surgical, Medical, Molecular Pathology and Critical Area, University of Pisa, Pisa, Italia. alessandro.antonelli@unipi.it.ORCID http://orcid.org/0000-0002-5211-6342
University of Pisa · ITMeyer Children's Hospital · ITAzienda Ospedaliera Universitaria Pisana · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of the present study is to analyze thyroglossal duct cyst (TGDC) histopathological features, with focus on "arborization", in a cohort of pediatric patients who underwent surgical removal, and evaluate a possible correlation with clinical recurrences.

methodsA retrospective analysis of all patients who underwent surgical resection for TGDC at the division of Pediatric Surgery of the University of Pisa from 2015 to 2020 was performed; for each patient, the following data were recorded: age, sex, clinical presentation, localization, size of the lesion, diagnostic tools, histopathological features, perioperative complications, recurrence and follow-up.

resultsWith respect to arborization, following histopathological analysis 25/30 patients (83.3%) presented thyroglossal duct branching. After a median follow-up of 3.5 years, only 2 out of 30 patients (6.7%), one male and one female, respectively aged 4 y.o. and 6 y.o., presented recurrence within one year from first surgery.

conclusionSurgery for TGDC remains a challenge for pediatric surgeons, while arborization was present in most of our cases which underwent surgery. With respect to the role of arborization, our study did not highlight sufficient conclusive data regarding their role in recurrence: instead, it showed wide resection as satisfactory, being the arborization present in most of the cases at histopathology.

Indexed as

Thyroglossal CystAdolescentChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMaleRecurrenceRetrospective StudiesTreatment OutcomeArborizationPediatric ageSistrunk’s procedureThyroglossal duct cyst

Identifiers

PMID38594507
PMCPMC11211129
OpenAlexW4394601177

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.