Evidence map›Paper›PMID 38594499›Full record

ReviewInternational journal of legal medicine2024

Exploring the role of the human microbiome in forensic identification: opportunities and challenges.

Lorenzo Franceschetti, Giorgia Lodetti, Alberto Blandino, Alberto Amadasi, Valentina Bugelli

Abstract readReview
In one paragraph

Review in International journal of legal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Effective use of skin microbiome signatures for fingerprint identification.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lorenzo Franceschetti *Institute of Legal Medicine, Department of Biomedical Sciences for Health, University of Milan, via Luigi Mangiagalli 37, Milan, 20133, Italy. lorenzo.franceschetti@unimi.it.ORCID http://orcid.org/0000-0003-0887-0708
Giorgia Lodetti *Institute of Legal Medicine, Department of Biomedical Sciences for Health, University of Milan, via Luigi Mangiagalli 37, Milan, 20133, Italy.
Alberto BlandinoVita-Salute San Raffaele University, Milan, Italy.
Alberto AmadasiInstitute of Legal Medicine and Forensic Sciences, University Medical Centre Charité, University of Berlin, Turmstr. 21, Building N, Berlin, 10559, Germany.
Valentina BugelliDepartment of Medicine and Surgery, Section of Forensic Medicine, University of Parma, Parma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Forensic microbiology is rapidly emerging as a novel tool for human identification. The human microbiome, comprising diverse microbial communities including fungi, bacteria, protozoa, and viruses, is unique to each individual, offering a new dimension to forensic investigations. While traditional identification methods primarily rely on DNA profiling and fingerprint analysis, they face limitations when complete DNA or fingerprints profiles are unattainable or degraded. In this context, the microbial signatures of the human skin microbiome present a promising alternative due to their resilience to environmental stresses and individual-specific composition. This review explores the potential of microbiome analysis in forensic human identification, evaluating its applications, advantages, limitations, and future prospects. The uniqueness of an individual's microbial community, particularly the skin microbiota, can provide distinctive biological markers for identification purposes, while technological advancements like 16 S rRNA sequencing and metagenomic shotgun sequencing are enhancing the specificity of microbial identification, enabling detailed analysis of these complex ecological communities. Despite these promising findings, current research has not yet achieved a level of identification probability that could establish microbial analysis as a stand-alone evidence tool. Therefore, it is presently considered ancillary to traditional methods, contributing to a more comprehensive biological profile of individuals.

Indexed as

MicrobiotaSkinDNA FingerprintingHumansMetagenomicsRNA, Ribosomal, 16SRNA, Ribosomal, 16SForensic identificationForensic microbiologyHuman microbiomeMicrobiota profilingPersonal identification

Identifiers

PMID38594499
PMCPMC11306296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.