ReviewNature reviews. Neuroscience2024
From compulsivity to compulsion: the neural basis of compulsive disorders.
Review in Nature reviews. Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review on Insomnia and Circadian Rhythms Desynchronization in Obsessive-Compulsive Disorder: From Childhood to Adulthood.Journal of sleep research · 2026Pooled it
- Global trends and research hotspots in the treatment of mental disorders with transcranial magnetic stimulation: a bibliometric analysis.Frontiers in psychiatry · 2025Pooled it
- Limited Efficacy of 3 mA Intensified tDCS of the Right Inferior Frontal Cortex for OCD Treatment: A Randomized, Double-Blind, Sham-Controlled Study.CNS neuroscience & therapeutics · 2026Trial
- Heterogeneous structural brain signatures of methamphetamine and ketamine use disorders revealed by normative modeling.Molecular psychiatry · 2026Article
- Closed-loop transcranial alternating current stimulation (tACS) reduces cue reactivity and improves inhibitory control in methamphetamine use disorder with frequency and timing specificity.Molecular psychiatry · 2026Article
- Impaired midfrontal‑motor theta phase synchronization characterizes maladaptive motivational behavior in people with obsessive‑compulsive disorder.PLoS biology · 2026Article
- Animal models relevant to digital technology-based disorders.Journal of behavioral addictions · 2026Article
- Behavioral inhibition/activation system in obsessive-compulsive disorder: brain morphometric correlates and treatment outcomes.Translational psychiatry · 2026Article
- Dissociating volatility and stochasticity reveals transdiagnostic computational signatures of psychopathology.bioRxiv : the preprint server for biology · 2026Article
- Parent- and child-reported executive functioning and response to psychotherapy in pediatric obsessive-compulsive disorder: Results from the TECTO study.European child & adolescent psychiatry · 2026Article
- Dissecting the interplay of model-based control, impulsivity and compulsivity on self-control in daily life.Scientific reports · 2026Article
- Neural Reward Processing in Digital Addiction: A Dynamical Systems Theory of Reward Instability.Brain sciences · 2026Article
- Superior colliculus modulates the compulsion in a model of addiction with foot-shock.Translational psychiatry · 2026Article
- Distinct cognitive and functional connectivity features from healthy cohorts can identify clinical obsessive-compulsive disorder.Molecular psychiatry · 2026Article
- Naturalistic Associations Between Childhood Maltreatment, Compulsivity, and Eating Disorder Symptoms Over a 12-Months Period Among Individuals With Anorexia Nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Bipolar Disorder as a Long-Term Risk Factor for Parkinson's Disease: A Nationwide Case-Control Study.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Learning Mechanisms in Alcohol Use Disorders.Addiction biology · 2026Review
- The informational dysregulation framework of addiction (IDFA): an information-processing model of relapse in opioid use disorder.Frontiers in psychiatry · 2026Article
- Comparison of neuro-metabolites in borderline and antisocial personality disorders: A study based on proton magnetic resonance spectroscopy.Personality neuroscience · 2026Article
- Sense of agency and addiction.Frontiers in psychology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Compulsive behaviour, an apparently irrational perseveration in often maladaptive acts, is a potential transdiagnostic symptom of several neuropsychiatric disorders, including obsessive-compulsive disorder and addiction, and may reflect the severe manifestation of a dimensional trait termed compulsivity. In this Review, we examine the psychological basis of compulsions and compulsivity and their underlying neural circuitry using evidence from human neuroimaging and animal models. Several main elements of this circuitry are identified, focused on fronto-striatal systems implicated in goal-directed behaviour and habits. These systems include the orbitofrontal, prefrontal, anterior cingulate and insular cortices and their connections with the basal ganglia as well as sensoriomotor and parietal cortices and cerebellum. We also consider the implications for future classification of impulsive-compulsive disorders and their treatment.
Indexed as
Identifiers
38594324What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.