Evidence map›Paper›PMID 38594036›Full record

Observational studyRespiratory care2024

Quantitative Computed Tomography and Response to Pronation in COVID-19 ARDS.

Francesco Zadek, Luca Berta, Giulia Zorzi, Stefania Ubiali, Amos Bonaiti, Giulia Tundo, Beatrice Brunoni, Francesco Marrazzo, Riccardo Giudici, Anna Rossi and 7 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Respiratory care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 0 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Francesco ZadekDepartment of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.
Luca BertaDepartment of Medical Physics, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Giulia ZorziMedical Physics, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy; and Department of Physics, INFN Milan Unit, Milan, Italy.
Stefania UbialiDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Amos BonaitiDepartment of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.
Giulia TundoDepartment of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.
Beatrice BrunoniDepartment of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.
Francesco MarrazzoDepartment of Anesthesia and Intensive Care Medicine, Niguarda Ca' Granda, Milan, Italy.
Riccardo GiudiciDepartment of Anesthesia and Intensive Care Medicine, Niguarda Ca' Granda, Milan, Italy.
Anna RossiDepartment of Anesthesia and Intensive Care Medicine, Niguarda Ca' Granda, Milan, Italy.
Francesco RizzettoDepartment of Radiology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Davide Paolo BernasconiSchool of Medicine and Surgery, Bicocca Bioinformatics Biostatistics and Bioimaging Center - B4, University of Milano-Bicocca, Monza, Italy.
Angelo VanzulliDepartment of Radiology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy; and Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy.
Paola Enrica ColomboDepartment of Medical Physics, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Roberto FumagalliDepartment of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy; and Department of Anesthesia and Intensive Care Medicine, Niguarda Ca' Granda, Milan, Italy.
Alberto TorresinDepartment of Medical Physics, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Thomas LangerDepartment of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy; and Department of Anesthesia and Intensive Care Medicine, Niguarda Ca' Granda, Milan, Italy. Thomas.Langer@unimib.it.
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITUniversity of Milano-Bicocca · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of prone position (PP) has been widespread during the COVID-19 pandemic. Whereas it has demonstrated benefits, including improved oxygenation and lung aeration, the factors influencing the response in terms of gas exchange to PP remain unclear. In particular, the association between baseline quantitative computed tomography (CT) scan results and gas exchange response to PP in invasively ventilated subjects with COVID-19 ARDS is unknown. The present study aimed to compare baseline quantitative CT results between subjects responding to PP in terms of oxygenation or CO

methodsThis was a single-center, retrospective observational study including critically ill, invasively ventilated subjects with COVID-19-related ARDS admitted to the ICUs of Niguarda Hospital between March 2020-November 2021. Blood gas samples were collected before and after PP. Subjects in whom the P

resultsOne hundred twenty-five subjects were enrolled, of which 116 (93%) were O

conclusionsMost subjects with COVID-19-related ARDS improved their oxygenation at the first pronation cycle. The study suggests that baseline quantitative CT scan data were not associated with the response to PP in oxygenation or CO

Indexed as

COVID-19LungPulmonary Gas ExchangeRespiration, ArtificialRespiratory Distress SyndromeTomography, X-Ray ComputedAgedBlood Gas AnalysisCarbon DioxideCritical IllnessFemaleHumansMaleMiddle AgedOxygenPatient PositioningCarbon DioxideOxygencomputed tomographycoronavirus SARSCOVID-19 ARDSlung complianceprone positionpulmonary gas exchangequantitative CT scan analysisventilation/perfusion scan

Identifiers

PMID38594036
PMCPMC11549634
OpenAlexW4394603817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.