Evidence map›Paper›PMID 38593468›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2024

LPA

Beth B McConnell, Zhongxing Liang, Chad Xu, Yiran Han, C Chris Yun

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Beth B McConnellDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States.ORCID 0009-0002-8435-3569
Zhongxing LiangDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States.
Chad XuDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States.
Yiran HanDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States.
C Chris YunDivision of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States.ORCID 0000-0002-5518-9870
Emory University · USUnited States Department of Veterans Affairs · US

Funding

The function of lysophosphatidic acid receptor LPA5R in intestinal inflammation and epithelial damageR01DK116799 · NIDDK · EMORY UNIVERSITY · PI YUN, CHANGHYON CHRIS · 2018 to 2022
$2.5M
Regulation of Human NHE3 by UbiquitinationR01DK107719 · NIDDK · EMORY UNIVERSITY · PI YUN, CHANGHYON CHRIS · 2016 to 2019
$1.4M
Role of Na+/H+ exchanger in diabetic diarrheaI01BX004459 · VA · VETERANS HEALTH ADMINISTRATION · PI YUN, CHANGHYON CHRIS · 2020 to 2024
–
Regulation of intestinal epithelial barrier and motility by the LPA1 receptor in the enteric nervous systemI01BX006369 · VA · VETERANS HEALTH ADMINISTRATION · PI YUN, CHANGHYON CHRIS · 2024 to 2025
–
BLRD VA I01 BX004459BLRD VA I01 BX006369HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM) R01DK107719NIDDK NIH HHS R01 DK107719NIDDK NIH HHS R01 DK116799U.S. Department of Veterans Affairs (VA) I01BX004459U.S. Department of Veterans Affairs (VA) I01BX006369
6 · The paper itself

Abstract

Lysophosphatidic acid (LPA) is a bioactive lipid molecule that regulates a wide array of cellular functions, including proliferation, differentiation, and survival, via activation of cognate receptors. The LPA

Indexed as

Intestinal MucosaReceptors, Lysophosphatidic AcidRegenerationSignal TransductionAnimalsApoptosisCell ProliferationIntestine, SmallLysophospholipidsMiceMice, KnockoutOrganoidsRadiation Injuries, ExperimentalStem CellsYAP-Signaling ProteinsLPAR5 protein, mouselysophosphatidic acidLysophospholipidsReceptors, Lysophosphatidic AcidYap1 protein, mouseYAP-Signaling ProteinsintestineirradiationLPAregenerationsurvival

Identifiers

PMID38593468
PMCPMC11376986
OpenAlexW4394594251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.