ArticleJMIR mental health2024
Assessing the Alignment of Large Language Models With Human Values for Mental Health Integration: Cross-Sectional Study Using Schwartz's Theory of Basic Values.
Article in JMIR mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- "It's Not Only Attention We Need": Systematic Review of Large Language Models in Mental Health Care.JMIR mental health · 2025Pooled it
- Exploring the application boundaries of LLMs in mental health: a systematic scoping review.Frontiers in psychology · 2025Pooled it
- Evidence, use cases, and implementation safeguards of large language models in primary care.Communications medicine · 2026Review
- Personality Constructs Predictions Beyond FFM/Big5: A Digital Phenotyping-Based Exploration.Journal of personality · 2026Article
- Deciphering AI-chatbots utilization in clinical practice, research and education among Chinese medical students in generative AI era: a cross-sectional study.BMC medical education · 2026Article
- Feasibility and acceptability of the MentiParent AI chatbot for training parental reflective functioning.Scientific reports · 2026Article
- Neurodivergent influenceability in agentic AI as a contingent solution to the AI alignment problem.PNAS nexus · 2026Article
- Evaluation of cross-ethnic emotion recognition capabilities in multimodal large language models using the reading the mind in the eyes test.Scientific reports · 2026Article
- Psychometric applications of generative artificial intelligence: Lifecycle, risks, and research agenda.PLOS mental health · 2026Review
- H3-MOSAIC: multimodal generative AI for semantic place detection from high-frequency GPS on H3 grids in mental health geomatics.International journal of health geographics · 2025Article
- Current applications and future directions in natural language processing for news media and mental health.Scientific reports · 2025Article
- Advancing youth co-design of ethical guidelines for AI-powered digital mental health tools.Nature. Mental health · 2025Article
- A controlled trial examining large Language model conformity in psychiatric assessment using the Asch paradigm.BMC psychiatry · 2025Article
- The Feasibility of Large Language Models in Verbal Comprehension Assessment: Mixed Methods Feasibility Study.JMIR formative research · 2025Article
- Responsible Design, Integration, and Use of Generative AI in Mental Health.JMIR mental health · 2025Article
- Transforming Perceptions: Exploring the Multifaceted Potential of Generative AI for People With Cognitive Disabilities.JMIR neurotechnology · 2025Article
- The externalization of internal experiences in psychotherapy through generative artificial intelligence: a theoretical, clinical, and ethical analysis.Frontiers in digital health · 2025Article
- Evaluation of large language models on mental health: from knowledge test to illness diagnosis.Frontiers in psychiatry · 2025Article
- An Ethical Perspective on the Democratization of Mental Health With Generative AI.JMIR mental health · 2024Article
- The use of Artificial Intelligence in Psychotherapy: Practical and Ethical Aspects.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2024Article
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Abstract
backgroundLarge language models (LLMs) hold potential for mental health applications. However, their opaque alignment processes may embed biases that shape problematic perspectives. Evaluating the values embedded within LLMs that guide their decision-making have ethical importance. Schwartz's theory of basic values (STBV) provides a framework for quantifying cultural value orientations and has shown utility for examining values in mental health contexts, including cultural, diagnostic, and therapist-client dynamics.
objectiveThis study aimed to (1) evaluate whether the STBV can measure value-like constructs within leading LLMs and (2) determine whether LLMs exhibit distinct value-like patterns from humans and each other.
methodsIn total, 4 LLMs (Bard, Claude 2, Generative Pretrained Transformer [GPT]-3.5, GPT-4) were anthropomorphized and instructed to complete the Portrait Values Questionnaire-Revised (PVQ-RR) to assess value-like constructs. Their responses over 10 trials were analyzed for reliability and validity. To benchmark the LLMs' value profiles, their results were compared to published data from a diverse sample of 53,472 individuals across 49 nations who had completed the PVQ-RR. This allowed us to assess whether the LLMs diverged from established human value patterns across cultural groups. Value profiles were also compared between models via statistical tests.
resultsThe PVQ-RR showed good reliability and validity for quantifying value-like infrastructure within the LLMs. However, substantial divergence emerged between the LLMs' value profiles and population data. The models lacked consensus and exhibited distinct motivational biases, reflecting opaque alignment processes. For example, all models prioritized universalism and self-direction, while de-emphasizing achievement, power, and security relative to humans. Successful discriminant analysis differentiated the 4 LLMs' distinct value profiles. Further examination found the biased value profiles strongly predicted the LLMs' responses when presented with mental health dilemmas requiring choosing between opposing values. This provided further validation for the models embedding distinct motivational value-like constructs that shape their decision-making.
conclusionsThis study leveraged the STBV to map the motivational value-like infrastructure underpinning leading LLMs. Although the study demonstrated the STBV can effectively characterize value-like infrastructure within LLMs, substantial divergence from human values raises ethical concerns about aligning these models with mental health applications. The biases toward certain cultural value sets pose risks if integrated without proper safeguards. For example, prioritizing universalism could promote unconditional acceptance even when clinically unwise. Furthermore, the differences between the LLMs underscore the need to standardize alignment processes to capture true cultural diversity. Thus, any responsible integration of LLMs into mental health care must account for their embedded biases and motivation mismatches to ensure equitable delivery across diverse populations. Achieving this will require transparency and refinement of alignment techniques to instill comprehensive human values.
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