Evidence map›Paper›PMID 38593225›Full record

ArticleJournal of the American Geriatrics Society2024

A scoping review of racial, ethnic, socioeconomic, and geographic disparities in the outcomes of older adults with cancer.

Nikesha Gilmore, Shakira J Grant, Traci N Bethea, Melody K Schiaffino, Heidi D Klepin, William Dale, Angela Hardi, Jeanne Mandelblatt, Supriya Mohile, Cancer and Aging Research Group

Open access · bronzeAbstract readScoping Review
In one paragraph

Article in Journal of the American Geriatrics Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Nikesha GilmoreDepartment of Surgery, Division of Supportive Care in Cancer, University of Rochester Medical Center, Rochester, New York, USA.ORCID https://orcid.org/0000-0002-5079-1723
Shakira J GrantDepartment of Medicine, Division of Hematology, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-8481-3046
Traci N BetheaOffice of Minority Health and Health Disparities Research and the Cancer Prevention and Control Program, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.
Melody K SchiaffinoDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, San Diego, California, USA.ORCID https://orcid.org/0000-0001-8519-8391
Heidi D KlepinDepartment of Hematology and Oncology, Comprehensive Cancer Center, Wake Forest University, Winston Salem, North Carolina, USA.
William DaleDepartment of Supportive Care Medicine, City of Hope, Duarte, California, USA.
Angela HardiBecker Medical Library, Washington University School of Medicine, St. Louis, Missouri, USA.
Jeanne MandelblattDepartment of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.
Supriya MohileDepartment of Medicine, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA.
Cancer and Aging Research Group
Georgetown University · USUniversity of Rochester Medical Center · USCity of Hope · USUniversity of California San Diego · USUniversity of North Carolina at Chapel Hill · USWake Forest University · USWashington University in St. Louis · US

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
UNC Oncology K12K12CA120780 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM · 2007 to 2026
$9.6M
Bio-behavioral Research At The Intersection of Cancer and AgingR35CA197289 · NCI · GEORGETOWN UNIVERSITY · PI MANDELBLATT, JEANNE · 2015 to 2021
$6.2M
Geriatric Oncology Research Infrastructure to Improve Clinical CareR33AG059206 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WILLIAM DALE, Heidi Diana Klepin · 2020 to 2026
$5.1M
Social Determinants of Health as Transducers of Cellular Aging: A New Multi-level Paradigm to Reduce Survivorship Disparities at the Intersection of Cancer and AgingR35CA283926 · NCI · GEORGETOWN UNIVERSITY · PI Jeanne Mandelblatt · 2023 to 2026
$3.7M
I-REACH (Infrastructure for REsearch on Cancer and Aging)R33AG075008 · NIA · GEORGETOWN UNIVERSITY · PI Lucile L. Adams-Campbell, Judith E Carroll · 2024 to 2026
$2.3M
A Patient-Oriented Research Program in Geriatric OncologyK24AG056589 · NIA · UNIVERSITY OF ROCHESTER · PI Supriya G. Mohile · 2018 to 2026
$1.5M
Mentoring the Next Generation of Geriatric Oncology Researchers in Patient-Oriented Research to Improve the Care of Older Adults with CancerK24AG055693 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WILLIAM DALE · 2018 to 2026
$1.4M
A Phase II Randomized Placebo Controlled Trial of Epigallocatechin-3-Gallate (EGCG) on Physical Frailty and Tumor Necrosis Factor-alpha and Associated Immune Markers in Older Cancer SurvivorsK01CA276257 · NCI · UNIVERSITY OF ROCHESTER · PI Nikesha Gilmore · 2023 to 2026
$674k
Improving age-related risk assessment and documentation for diverse older adults with cancerK01AG068592 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Melody K Schiaffino · 2022 to 2026
$673k
An assessment of whether aspirin and/or vitamin D improves breast cancer outcomes in Black women and the modifying effect of genetic variantsK01CA212056 · NCI · GEORGETOWN UNIVERSITY · PI BETHEA, TRACI N. · 2017 to 2021
$656k
I-REACH: Infrastructure for Research in Equity, Aging, Cancer and HealthR21AG075008 · NIA · GEORGETOWN UNIVERSITY · PI ADAMS-CAMPBELL, LUCILE LAUREN, CARROLL, JUDITH E · 2022 to 2023
$475k
NCI NIH HHS K01 CA212056NCI NIH HHS K01CA212056NCI NIH HHS K01 CA276257NCI NIH HHS K01CA276257NCI NIH HHS K12 CA120780NCI NIH HHS K12CA120780NCI NIH HHS R351CA97289NCI NIH HHS R35 CA197289NCI NIH HHS R35 CA283926NCI NIH HHS R35CA283926NCI NIH HHS UG1 CA189961NIA NIH HHS K01 AG068592NIA NIH HHS K01AG068592NIA NIH HHS K24 AG055693NIA NIH HHS K24 AG056589NIA NIH HHS K24AG056589NIA NIH HHS R03 AG074030NIA NIH HHS R03AG074030NIA NIH HHS R21 AG075008NIA NIH HHS R21AG075008NIA NIH HHS R33 AG059206NIA NIH HHS R33 AG075008NIMHD NIH HHS L32 MD013114
6 · The paper itself

Abstract

introductionCancer health disparities are widespread. Nevertheless, the disparities in outcomes among diverse survivors of cancer ages 65 years and older ("older") have not been systematically evaluated.

methodsWe conducted a scoping review of original research articles published between January 2016 and September 2023 and indexed in Medline (Ovid), Embase, Scopus, and CINAHL databases. We included studies evaluating racial, ethnic, socioeconomic disadvantaged, geographic, sexual and gender, and/or persons with disabilities disparities in treatment, survivorship, and mortality among older survivors of cancer. We excluded studies with no a priori aims related to a health disparity, review articles, conference proceedings, meeting abstracts, studies with unclear methodologies, and articles in which the disparity group was examined only as an analytic covariate. Two reviewers independently extracted data following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis reporting guidelines.

resultsAfter searching and removing duplicates, 2573 unique citations remained and after screening 59 articles met the inclusion criteria. Many investigated more than one health disparity, and most focused on racial and ethnic (n = 44) or socioeconomic (n = 25) disparities; only 10 studies described geographic disparities, and none evaluated disparities in persons with disabilities or due to sexual and gender identity. Research investigating disparities in outcomes among diverse older survivors of cancer is increasing gradually-68% of eligible articles were published between 2020 and 2023. Most studies focused on the treatment phase of care (n = 28) and mortality (n = 26), with 16 examined disparities in survivorship, symptoms, or quality of life. Most research was descriptive and lacked analyses of potential underlying mechanisms contributing to the reported disparities.

conclusionLittle research has evaluated the effect of strategies to reduce health disparities among older patients with cancer. This lack of evidence perpetuates cancer inequities and leaves the cancer care system ill equipped to address the unique needs of the rapidly growing and increasingly diverse older adult cancer population.

Indexed as

Healthcare DisparitiesNeoplasmsSocioeconomic FactorsAgedCancer SurvivorsEthnicityFemaleHealth Status DisparitiesHumansMaleRacial Groupsdisparitiesolder adults with cancer

Identifiers

PMID38593225
PMCPMC11187671
OpenAlexW4394596318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.