ReviewPlants (Basel, Switzerland)2024
Impact of Heavy Metal Pollution in the Environment on the Metabolic Profile of Medicinal Plants and Their Therapeutic Potential.
Review in Plants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Toxic Metal in Plant-Based Therapeutics: Contamination Pathways, Oxidative Stress Induction, and Onset of Disease.TheScientificWorldJournal · 2026Pooled it
- Mapping of plant-fungal interactions on agriculture perception: a bibliometric analysis and systematic review.Frontiers in microbiology · 2025Pooled it
- Endophytic Fungal Metabolites as Modulators of Key Signaling Pathways in Chronic Diseases and Aging.Antibiotics (Basel, Switzerland) · 2026Review
- Green-synthesized lanthanum nanostructures modulate redox balance and phytochemical responses in lead-stressed Zataria multiflora.BMC plant biology · 2026Article
- Elemental Profiling and Health Risk Assessment of Aromatic Oils Used for Oral and Topical Applications.Biological trace element research · 2026Article
- Coupled regulation effects of sanqi-pine intercropping systems on soil fertility and heavy metals mediated by ammonia-oxidizing microorganisms.BMC plant biology · 2026Article
- Selenium Nanobiostimulants Attenuate Copper-Induced Oxidative Damage inPlants (Basel, Switzerland) · 2026Article
- Integrated Biochemical and Ultrastructural Responses ofPlants (Basel, Switzerland) · 2026Article
- Article
- Article
- Cancer and Environmental Xenobiotics: Mechanisms, Controversies, and Innovations.Journal of xenobiotics · 2025Review
- Assessing the Ecotoxicological Effects of Emerging Drug and Dye Pollutants on Plant-Soil Systems Pre- and Post-Photocatalytic Wastewater Treatment.Plants (Basel, Switzerland) · 2025Review
- Organic versus conventional saffron production: apocarotenoid content and heavy metal contamination in Iran.Scientific reports · 2025Article
- Effect of citrulline seed priming on growth, photosynthesis, redox equilibrium, secondary metabolic enzymes, metal sequestration and nutrient acquisition in sunflower (Helianthus annuus L.) under chromium toxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- A review on simultaneous use of microbes and biochar for removal of toxic heavy metals: Recent updates and future outlooks.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Review
- Review
- Cellular strategies for surviving the alpine extremes: methylerythritol phosphate pathway-driven isoprenoid biosynthesis and stress resilience.Protoplasma · 2025Review
- Targeting Cardiotoxicity Induced by Environmental Toxins: The Role of Natural Products.Cardiovascular toxicology · 2025Review
- Multiple Strategies for the Application of Medicinal Plant-Derived Bioactive Compounds in Controlling Microbial Biofilm and Virulence Properties.Antibiotics (Basel, Switzerland) · 2025Review
- Impact of pollution on microbiological dynamics in the pistil stigmas of Orobanche lutea flowers (Orobanchaceae).Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The paper provides a comprehensive examination of heavy metal stress on medicinal plants, focusing on its impact on antioxidant capacity and biosynthetic pathways critical to their therapeutic potential. It explores the complex relationship between heavy metals and the physiological and biochemical responses of medicinal plants, highlighting how metal stress disrupts biosynthetic pathways, altering concentrations of secondary metabolites. This disruption may compromise the overall quality and efficacy of medicinal plants, requiring a holistic understanding of its cumulative impacts. Furthermore, the study discusses the potential of targeted genetic editing to enhance plant resilience against heavy metal stress by manipulating genes associated with antioxidant defenses. This approach represents a promising frontier in safeguarding medicinal plants in metal-contaminated environments. Additionally, the research investigates the role of phytohormone signaling in plant adaptive mechanisms to heavy metal stress, revealing its influence on biochemical and physiological responses, thereby adding complexity to plant adaptation. The study underscores the importance of innovative technologies and global cooperation in protecting medicinal plants' therapeutic potential and highlights the need for mitigation strategies to address heavy metal contamination effectively.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.