Evidence map›Paper›PMID 38592748›Full record

ArticlePlants (Basel, Switzerland)2024

Eucalypt Extracts Prepared by a No-Waste Method and Their 3D-Printed Dosage Forms Show Antimicrobial and Anti-Inflammatory Activity.

Oleh Koshovyi, Mykola Komisarenko, Tatyana Osolodchenko, Andrey Komissarenko, Reet Mändar, Siiri Kõljalg, Jyrki Heinämäki, Ain Raal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Oleh KoshovyiInstitute of Pharmacy, Faculty of Medicine, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.ORCID 0000-0001-9545-8548
Mykola KomisarenkoPharmacognosy Department, The National University of Pharmacy, 53 Pushkinska St., 61002 Kharkiv, Ukraine.
Tatyana OsolodchenkoState Institution "I.Mechnikov Institute of Microbiology and Immunology, National Academy of Medical Sciences of Ukraine", 14-16, Pushkinskaya St., 61057 Kharkov, Ukraine.
Andrey KomissarenkoPharmacognosy Department, The National University of Pharmacy, 53 Pushkinska St., 61002 Kharkiv, Ukraine.
Reet MändarDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Ravila 19, 50411 Tartu, Estonia.ORCID 0000-0002-9747-3618
Siiri KõljalgDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Ravila 19, 50411 Tartu, Estonia.
Jyrki HeinämäkiInstitute of Pharmacy, Faculty of Medicine, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.ORCID 0000-0002-5996-5144
Ain RaalInstitute of Pharmacy, Faculty of Medicine, University of Tartu, Nooruse 1, 50411 Tartu, Estonia.ORCID 0000-0001-8731-7366
National University of Pharmacy · UAUniversity of Tartu · EENational Academy of Medical Sciences of Ukraine · UATartu University Hospital · EE

Funding

CurifyLabs VMVFA22189Estonian Ministry of Education and Research KOGU-HUMBEstonian Research Council PRG1903European Union in the MSCA4Ukraine project 1232466
6 · The paper itself

Abstract

The pharmaceutical industry usually utilizes either hydrophobic or hydrophilic substances extracted from raw plant materials to prepare a final product. However, the waste products from the plant material still contain biologically active components with the opposite solubility. The aim of this study was to enhance the comprehensive usability of plant materials by developing a new no-waste extraction method for eucalypt leaves and by investigating the phytochemical and pharmacological properties of eucalypt extracts and their 3D-printed dosage forms. The present extraction method enabled us to prepare both hydrophobic soft extracts and hydrophilic (aqueous) dry extracts. We identified a total of 28 terpenes in the hydrophobic soft extract. In the hydrophilic dry extract, a total of 57 substances were identified, and 26 of them were successfully isolated. The eucalypt extracts studied showed significant antimicrobial activity against

Indexed as

aqueous gelcomplex processingeucalypt leaves extractphenolicspolyethylene oxidesemi-solid extrusion 3D printingterpenes

Identifiers

PMID38592748
PMCPMC10976152
OpenAlexW4392545627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.