ReviewJournal of clinical medicine2024
Management of Melasma: Laser and Other Therapies-Review Study.
Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy and safety of Q-switched laser combined with intense pulsed light in treating melasma: a meta-analysis.Frontiers in medicine · 2026Pooled it
- Comparison of The efficacy and safety of fractional erbium: YAG laser in combination with Tranexamic acid delivery by different methods versus Tranexamic acid alone: A systematic review and meta-analysis.Archives of dermatological research · 2025Pooled it
- Efficacy of Non-Ablative Fractional Laser Combined With Tranexamic Acid in Melasma Treatment: A Randomized Split-Face Trial.Journal of cosmetic dermatology · 2025Trial
- [Q-switched Nd:YAG 1064 nm laser combined with topical metformin lotion for treatment of chloasma in mice].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Global consensus on the management of melanin hyperpigmentation disorders.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026Review
- Innovations in Refractory Melasma: Mechanism-Based Management and Emerging Therapeutic Strategies.Cureus · 2026Review
- Improved clinical efficacy of melasma with combination therapy of intense pulsed light and tranexamic acid: A retrospective analysis.Medicine · 2026Article
- Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology.Journal of cosmetic dermatology · 2026Review
- Subtype-Specific Response to Fractional-Mode Q-Switched Ruby Laser in Melasma: A Prospective Single-Blind Clinical Study Using Clinical and Noninvasive Imaging Assessments.Clinical, cosmetic and investigational dermatology · 2026Article
- Efficacy and Safety of Different Treatments for Melasma: Network Meta-Analysis of Updated Data.Diseases (Basel, Switzerland) · 2025Review
- Efficacy and Tolerability of a New Facial 2-Mercaptonicotinoyl Glycine-Containing Depigmenting Serum Versus Hydroquinone 4% over 3-Month Treatment of Facial Melasma.Dermatology and therapy · 2025Article
- The Genetics and Evolution of Human Pigmentation.Biology · 2025Review
- Effectiveness of the Er:YAG Laser in Snoring Treatment Based on Systematic Review and Meta-Analysis Results.Journal of clinical medicine · 2025Review
- Relationship Between Facial Melasma and Ocular Photoaging Diseases.Medical sciences (Basel, Switzerland) · 2025Article
- A Scoping Review on Melasma Treatments and Their Histopathologic Correlates.Dermatopathology (Basel, Switzerland) · 2025Review
- Article
- Skin Structure, Physiology, and Pathology in Topical and Transdermal Drug Delivery.Pharmaceutics · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melasma is a commonly occurring pigmented skin condition that can significantly affect one's appearance, described as symmetric hyperpigmentation that presents as irregular brown to gray-brown macules on various facial areas, such as the cheeks, forehead, nasal bridge, and upper lip, along with the mandible and upper arms. Due to its complex pathogenesis and recurrent nature, melasma management is challenging and the outcomes following treatment are not always deemed satisfactory. Solely treating hyperpigmentation may prove ineffective unless paired with regenerative techniques and photoprotection, since one of the main reasons for recurrence is sun exposure. Hence, the treatment protocol starts with addressing risk factors, implementing stringent UV protection, and then treatment using different strategies, like applying topical treatments, employing chemical peels, laser and light therapies, microneedling, and systemic therapy. This review aims to provide a summary of the effectiveness and safety of the frequently employed laser and light therapies for treating melasma, focusing on laser therapy as a treatment for melasma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.