Evidence map›Paper›PMID 38592526›Full record

ArticleAdvances and technical standards in neurosurgery2024

Toward the "Perfect" Shunt: Historical Vignette, Current Efforts, and Future Directions.

Anthony Podgoršak, Fabian Flürenbrock, Nina Eva Trimmel, Leonie Korn, Markus Florian Oertel, Lennart Stieglitz, Sandra Fernandes Dias, Melanie Michaela Hierweger, Melanie Zeilinger, Miriam Weisskopf and 1 more

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Article in Advances and technical standards in neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anthony PodgoršakProduct Development Group Zurich, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.
Fabian FlürenbrockInstitute for Dynamic Systems and Control, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.
Nina Eva TrimmelCenter for Preclinical Development, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Leonie KornInstitute for Dynamic Systems and Control, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.
Markus Florian OertelDepartment of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Lennart StieglitzDepartment of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Sandra Fernandes DiasDepartment of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Melanie Michaela HierwegerCenter for Preclinical Development, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Melanie ZeilingerInstitute for Dynamic Systems and Control, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.
Miriam WeisskopfCenter for Preclinical Development, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Marianne Schmid DanersInstitute for Dynamic Systems and Control, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland. marischm@ethz.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a concept, drainage of excess fluid volume in the cranium has been around for more than 1000 years. Starting with the original decompression-trepanation of Abulcasis to modern programmable shunt systems, to other nonshunt-based treatments such as endoscopic third ventriculostomy and choroid plexus cauterization, we have come far as a field. However, there are still fundamental limitations that shunts have yet to overcome: namely posture-induced over- and underdrainage, the continual need for valve opening pressure especially in pediatric cases, and the failure to reinstall physiologic intracranial pressure dynamics. However, there are groups worldwide, in the clinic, in industry, and in academia, that are trying to ameliorate the current state of the technology within hydrocephalus treatment. This chapter aims to provide a historical overview of hydrocephalus, current challenges in shunt design, what members of the community have done and continue to do to address these challenges, and finally, a definition of the "perfect" shunt is provided and how the authors are working toward it.

Indexed as

HydrocephalusProstheses and ImplantsAmbulatory Care FacilitiesBehavior TherapyCathetersChildHumansCerebrospinal fluidHydrocephalusIntracranial pressureNeurosurgeryPhysiologySheep modelShunt

Identifiers

PMID38592526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.