Evidence map›Paper›PMID 38592378›Full record

ArticleBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2024

Synthesis, theoretical analysis, and biological properties of a novel tridentate Schiff base palladium (II) complex.

Samira Jahangiry, Maryam Lashanizadegan, Pouneh Sadat Pourhosseini, Mansoureh Zahedi-Tabrizi

Abstract read
PubMed Publisher
In one paragraph

Article in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samira JahangiryDepartment of Inorganic Chemistry, Faculty of Chemistry, Alzahra University, Tehran, Iran.ORCID http://orcid.org/0009-0002-5163-9616
Maryam LashanizadeganDepartment of Inorganic Chemistry, Faculty of Chemistry, Alzahra University, Tehran, Iran. M_lashani@alzahra.ac.ir.ORCID http://orcid.org/0000-0001-9492-3495
Pouneh Sadat Pourhosseini, Tehran, Iran.ORCID http://orcid.org/0000-0003-1666-9166
Mansoureh Zahedi-TabriziDepartment of Physical Chemistry and Nanochemistry, Faculty of Chemistry, Alzahra University, Tehran, Iran.ORCID http://orcid.org/0000-0002-0448-1548

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schiff base complexes play a crucial role in bioinorganic chemistry. A novel curcumin/phenylalanine tridentate Schiff base ligand and its palladium (II) complex were synthesized so that they were stable in aqueous buffer. The structure of the complex was investigated using a variety of methods, including DFT, NBO analysis, FMOs, and MESP. The interaction of the complex with a plasmid (pUC19) and CT-DNA was studied. The anticancer, antibacterial, and antioxidant activities of the complex were examined. The statistical analysis of the MTT assay was compared using the 1-way ANOVA and Tukey test. Results showed that the complexes were stable in aqueous buffer, pH 8. The extrinsic fluorescence emission of the plasmid and CT-DNA was quenched while interacting with the complex. The complex had an IC

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsAntioxidantsCoordination ComplexesEscherichia coliMicrobial Sensitivity TestsPalladiumSchiff BasesStaphylococcus aureusBiphenyl CompoundsCell ProliferationCurcuminDensity Functional TheoryDNADrug Screening Assays, AntitumorHumans1,1-diphenyl-2-picrylhydrazylAnti-Bacterial AgentsAntineoplastic AgentsAntioxidantsBiphenyl CompoundsCoordination ComplexesCurcuminDNAPalladiumPicratesSchiff BasesCurcuminDFTDNA bindingFluorescence quenchingPalladiumSchiff base

Identifiers

PMID38592378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.