Evidence map›Paper›PMID 38592175›Full record

ArticleJournal of clinical medicine2024

Long-Term Outcomes in Two-Year Follow-Up after Primary Treatment in Patients with a Prior Venous Thromboembolic Event: A Prospective, Observational, Real-Life Study.

Gualtiero Palareti, Emilia Antonucci, Eugenio Bucherini, Antonella Caronna, Antonio Chistolini, Angela Di Giorgio, Rosella Di Giulio, Anna Falanga, Vittorio Fregoni, Mariagrazia Garzia and 13 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Gualtiero PalaretiFondazione Arianna Anticoagulazione, 40138 Bologna, Italy.
Emilia AntonucciFondazione Arianna Anticoagulazione, 40138 Bologna, Italy.ORCID 0000-0001-9185-2046
Eugenio BucheriniSS Medicina Vascolare e Angiologia, AUSL Romagna, 48121 Ravenna, Italy.
Antonella CaronnaCentro per la Diagnosi e la Sorveglianza della Malattia Tromboembolica, UO Medicina Interna D'urgenza, Azienda Ospedaliero Universitaria Policlinico di Modena, Ospedale Civile Baggiovara, 41124 Modena, Italy.
Antonio ChistoliniDipartimento di Medicina Traslazionale e di Precisione Sapienza Università di Roma, 00197 Roma, Italy.ORCID 0000-0002-2593-1376
Angela Di GiorgioAngiologia Diagnostica Vascolare Non Invasiva, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Rosella Di GiulioU.O. Programma Dipartimentale di Ecografia-AUSL, 40133 Bologna, Italy.
Anna FalangaSchool of Medicine, Università di Milano Bicocca, 20126 Milano, Italy.ORCID 0000-0002-5007-3457
Vittorio FregoniU.O.C. Medicina Generale, Ospedale di Sondalo, ASST della Valtellina e dell'Alto Lario, 23035 Sondalo, Italy.
Mariagrazia GarziaUOC Ematologia-Trapianto Cellule Staminali, Azienda Ospedaliera S.Camillo-Forlanini, 00152 Roma, Italy.ORCID 0000-0002-0091-3112
Daniela MastroiacovoUOSD Angiologia e Diagnostica Vascolare, Ospedale SS Filippo e Nicola, Avezzano (L'Aquila), 67051 L'Aquila, Italy.
Marco MarzoloUOS Angiologia Medica, Ospedale di Rovigo, 45100 Rovigo, Italy.
Roberta PancaniU.O. Pneumologia, Dipartimento Cardiotoraco-Vascolare, Azienda Ospedaliero-Universitaria Pisana, Ospedale di Cisanello, 56126 Pisa, Italy.ORCID 0000-0001-6835-0937
Daniele PastoriDepartment of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00197 Roma, Italy.ORCID 0000-0001-6357-5213
Gian Marco PoddaMedicina Generale 2, ASST Santi Paolo e Carlo, Università degli Studi di Milano, 20142 Milano, Italy.
Anna Maria RigoniUOC di Angiologia, Azienda Ospedaliero Universitaria Integrata, 37126 Verona, Italy.
Luigi RiaUO Medicina Interna, Presidio Ospedaliero di Gallipoli (Lecce), 73014, Gallipoli, Italy.
Piera SiveraS.C.D.U. EMATOLOGIA Azienda Ospedaliera Ordine Mauriziano, 10128 Torino, Italy.
Sophie TestaCentro Emostasi e Trombosi, ASST Cremona, 26100 Cremona, Italy.
Adriana VisonàUOC Angiologia, Dipartimento di Medicina Clinica, Azienda ULSS 2 Marca Trevigiana, Ospedale San Giacomo Apostolo, 31033 Castelfranco Veneto, Italy.
Roberto ParisiUOSD Ipertensione e Patologie Endocrine Metaboliche Angiologiche, Ospedale SS. Giovanni e Paolo, 30122 Venezia, Italy.
Daniela PoliSOD Malattie Aterotrombotiche, Azienda Ospedaliero Universitaria-Careggi, 50134 Firenze, Italy.
On Behalf Of The Start Post Vte Investigators

Funding

Fondazione Arianna Anticoagulazione XXX
6 · The paper itself

Abstract

backgroundPatients with acute venous thromboembolism (VTE) need anticoagulation (AC) therapy for at least 3/6 months (primary treatment); after that period, they should receive a decision on the duration of therapy.

methodsThis study examined the complications occurring during two years of follow-up (FU) in patients with a first VTE who were recruited in 20 clinical centers and had discontinued or prolonged AC. They were included in the START2-POST-VTE prospective observational study.

resultsA total of 720 patients (53.5% males) who, after the completion of primary treatment, had received the decision to continue (

conclusionPhysicians' decisions about AC duration were independent of the unprovoked/provoked nature of the index event. The bleeding rate was higher in patients who continued AC using standard-dose DOACs. Surprisingly, the rate of thrombotic recurrence was not different between those who continued or discontinued AC. Randomized studies comparing different procedures to decide on the duration of AC after a first VTE are needed.

Indexed as

anticoagulant treatmentbleedinglong-term follow-uprecurrencevenous thromboembolism

Identifiers

PMID38592175
PMCPMC10931842

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.