Evidence map›Paper›PMID 38592155›Full record

ArticleJournal of clinical medicine2024

Embryo Transfer Procedural Parameters Do Not Predict IVF Cycle Outcome.

Konstantinos Sfakianoudis, Evangelos Maziotis, Anna Trypidi, Sokratis Grigoriadis, Terpsithea Vaxevanoglou, Irene Angeli, Anna Rapani, Amalia Kotsifaki, Kalliopi Pistola, Agni Pantou and 3 more

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Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Konstantinos SfakianoudisGenesis Athens Clinic, Centre for Human Reproduction, Papanikoli, 15232 Athens, Greece.
Evangelos MaziotisDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-6717-166X
Anna TrypidiDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Sokratis GrigoriadisDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-1861-8701
Terpsithea VaxevanoglouGenesis Athens Clinic, Centre for Human Reproduction, Papanikoli, 15232 Athens, Greece.
Irene AngeliGenesis Athens Clinic, Centre for Human Reproduction, Papanikoli, 15232 Athens, Greece.
Anna RapaniDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0001-7636-5848
Amalia KotsifakiDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Kalliopi PistolaDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-8798-7914
Agni PantouGenesis Athens Clinic, Centre for Human Reproduction, Papanikoli, 15232 Athens, Greece.ORCID 0000-0003-3224-5646
Konstantinos DafopoulosDepartment of Obstetrics and Gynecology, School of Health Sciences, Faculty of Medicine, University of Thessaly, 41500 Larisa, Greece.ORCID 0000-0001-9991-8097
Konstantinos PantosGenesis Athens Clinic, Centre for Human Reproduction, Papanikoli, 15232 Athens, Greece.
Mara SimopoulouDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-1000-9100

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundthis study aims to assess the effect of embryo transfer (ET) performance parameters of a technical nature on IVF outcome.

methodsA total of 1417 ETs from a single IVF center were included in this prospective observational study. The parameters investigated were as follows: the presence of cervical mucus post catheter withdrawal, the presence of blood, catheter reload, the employment of a tenaculum and stylet, catheter resistance as experienced by the physician and patient discomfort.

resultsWhen ET performance parameters were associated with clinical outcomes on a singular level, none of the ET parameters presented with any statistical significance. The evaluation of covariates indicated that the number and the quality of transferred embryos, as well as maternal age, exerted a statistically significant effect on clinical outcomes. In a multivariate analysis, only the presence of mucus along with significant catheter resistance presented with statistical significance; however, when adjusting for covariates, this combination showed no statistically significant effect on clinical outcomes.

conclusionsthe results indicate that the time-consuming process of recording and analyzing ET performance parameters fails to offer any additional value in predicting the cycle's outcome, while factors like embryo quality and number, as well as maternal age, seem to be the sole robust predictive factors of an IVF cycle.

Indexed as

assisted reproductionembryo transferIVFoutcomepre-implantation embryo

Identifiers

PMID38592155
PMCPMC10931750

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