Evidence map›Paper›PMID 38592057›Full record

ArticleJournal of clinical medicine2024

Validation of SeptiCyte RAPID to Discriminate Sepsis from Non-Infectious Systemic Inflammation.

Robert Balk, Annette M Esper, Greg S Martin, Russell R Miller, Bert K Lopansri, John P Burke, Mitchell Levy, Steven Opal, Richard E Rothman, Franco R D'Alessio and 23 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05469048 (Near Patient Molecular Testing in Sepsis), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05469048 completednot on this map

Near Patient Molecular Testing in Sepsis

TypeobservationalSponsorImmunexpressRan2020 to 2022Enrolled63ConditionsSepsis, Systemic Inflammatory Response Syndrome
3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Diagnostic accuracy of SeptiCyte® RAPID to discriminate sepsis from non-infectious critical illness in patients meeting sepsis criteria according to sepsis-3 definition at ICU admission.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Observational
  6. Article
  7. Observational
  8. Article
  9. Review
  10. Review
  11. Review
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Likelihood of blood culture positivity using SeptiCyte RAPID.medRxiv : the preprint server for health sciences · 2025
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Robert BalkRush Medical College and Rush University Medical Center, Chicago, IL 60612, USA.
Annette M EsperGrady Memorial Hospital and Emory University School of Medicine, Atlanta, GA 30322, USA.
Greg S MartinGrady Memorial Hospital and Emory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0000-0002-9684-7593
Russell R MillerFirstHealth of the Carolinas, Pinehurst, NC 28374, USA.
Bert K LopansriIntermountain Medical Center, Murray, UT 84107, USA.
John P BurkeIntermountain Medical Center, Murray, UT 84107, USA.
Mitchell LevyWarren Alpert Medical School, Brown University, Providence, RI 02912, USA.
Steven OpalWarren Alpert Medical School, Brown University, Providence, RI 02912, USA.
Richard E RothmanSchool of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Franco R D'AlessioSchool of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Venkataramana K SidhayeSchool of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Neil R AggarwalAnschutz Medical Campus, University of Colorado, Denver, CO 80045, USA.ORCID 0000-0002-0922-8824
Jared A GreenbergRush Medical College and Rush University Medical Center, Chicago, IL 60612, USA.
Mark YoderRush Medical College and Rush University Medical Center, Chicago, IL 60612, USA.
Gourang PatelRush Medical College and Rush University Medical Center, Chicago, IL 60612, USA.
Emily GilbertLoyola University Medical Center, Maywood, IL 60153, USA.
Jorge P ParadaLoyola University Medical Center, Maywood, IL 60153, USA.
Majid AfsharSchool of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA.
Jordan A KempkerGrady Memorial Hospital and Emory University School of Medicine, Atlanta, GA 30322, USA.
Tom van der PollAmsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Marcus J SchultzAmsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0003-3969-7792
Brendon P SciclunaCentre for Molecular Medicine and Biobanking, University of Malta, Msida MSD 2080, Malta.ORCID 0000-0003-2826-0341
Peter M C Klein KlouwenbergFundashon Mariadal, Kralendijk, Bonaire, Netherlands Antilles.
Janice LieblerKeck Hospital of University of Southern California (USC), Los Angeles, CA 90033, USA.
Emily BlodgetKeck Hospital of University of Southern California (USC), Los Angeles, CA 90033, USA.
Santhi KumarKeck Hospital of University of Southern California (USC), Los Angeles, CA 90033, USA.
Krupa NavalkarImmunexpress Inc., Seattle, DC 98109, USA.
Thomas D YagerImmunexpress Inc., Seattle, DC 98109, USA.ORCID 0000-0002-2341-2353
Dayle SampsonImmunexpress Inc., Seattle, DC 98109, USA.
James T KirkImmunexpress Inc., Seattle, DC 98109, USA.
Silvia CermelliImmunexpress Inc., Seattle, DC 98109, USA.
Roy F DavisImmunexpress Inc., Seattle, DC 98109, USA.
Richard B BrandonImmunexpress Inc., Seattle, DC 98109, USA.

Funding

Immunexpress, Inc. no grant number available
6 · The paper itself

Abstract

(1)

Indexed as

diagnosishost responsesepsissepsis scoring systemsSIRS

Identifiers

PMID38592057
PMCPMC10931699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.