Evidence map›Paper›PMID 38592034›Full record

ArticleDiabetes care2024

Timing of Moderate to Vigorous Physical Activity, Mortality, Cardiovascular Disease, and Microvascular Disease in Adults With Obesity.

Angelo Sabag, Matthew N Ahmadi, Monique E Francois, Svetlana Postnova, Peter A Cistulli, Luigi Fontana, Emmanuel Stamatakis

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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  10. Assessing the causal impact of leisure-time physical activity and screen time on lifespan: a Mendelian randomization study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Article
  11. Accelerometer-measured weekly and diurnal moderate-to-vigorous physical activity patterns and incident osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
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4 · The record

Corrections and comments

  • Commented on by
    2024
5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Angelo SabagCharles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-0195-7029
Matthew N AhmadiCharles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-3115-338X
Monique E FrancoisSchool of Medical, Indigenous and Health Sciences, University of Wollongong, Wollongong, New South Wales, Australia.ORCID 0000-0001-9518-0750
Svetlana PostnovaCharles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.
Peter A CistulliCharles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-7920-4924
Luigi FontanaCharles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-8500-5537
Emmanuel StamatakisCharles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-7323-3225
The University of Sydney · AUUniversity of Wollongong · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the association between timing of aerobic moderate to vigorous physical activity (MVPA) and risk of cardiovascular disease (CVD), microvascular disease (MVD), and all-cause mortality in adults with obesity and a subset with obesity and type 2 diabetes (T2D). RESEARCH DESIGN AND

methodsParticipants included adults with obesity (BMI ≥30 kg/m2) and a subset of those with T2D from the UK Biobank accelerometry substudy. Aerobic MVPA was defined as bouts of MVPA lasting ≥3 continuous minutes. Participants were categorized into morning, afternoon, or evening MVPA based on when they undertook the majority of their aerobic MVPA. The reference group included participants with an average of less than one aerobic MVPA bout per day. Analyses were adjusted for established and potential confounders.

resultsThe core sample included 29,836 adults with obesity, with a mean age of 62.2 (SD 7.7) years. Over a mean follow-up period of 7.9 (SD 0.8) years, 1,425 deaths, 3,980 CVD events, and 2,162 MVD events occurred. Compared with activity in the reference group, evening MVPA was associated with the lowest risk of mortality (hazard ratio [HR] 0.39; 95% CI 0.27, 0.55), whereas afternoon (HR 0.60; 95% CI 0.51, 0.71) and morning MVPA (HR 0.67; 95% CI 0.56, 0.79) demonstrated significant but weaker associations. Similar patterns were observed for CVD and MVD incidence, with evening MVPA associated with the lowest risk of CVD (HR 0.64; 95% CI 0.54, 0.75) and MVD (HR 0.76; 95% CI 0.63, 0.92). Findings were similar in the T2D subset (n = 2,995).

conclusionsAerobic MVPA bouts undertaken in the evening were associated with the lowest risk of mortality, CVD, and MVD. Timing of physical activity may play a role in the future of obesity and T2D management.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2AccelerometryAdultExerciseHumansMiddle AgedObesity

Identifiers

PMID38592034
PMCPMC11043226
OpenAlexW4394604292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.