Evidence map›Paper›PMID 38591913›Full record

ArticleJournal of bacteriology2024

Siderophore-mediated iron acquisition by

Ashish Kumar, Somnath Chakravorty, Taihao Yang, Thomas A Russo, Salete M Newton, Phillip E Klebba

Abstract read
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Influence of iron uptake systems on cefiderocol activity inAntimicrobial agents and chemotherapy · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. <p>Molecular medicine reports · 2026
    Review
  13. Article
  14. Characterization and pathogenic mechanisms of aFrontiers in microbiology · 2026
    Article
  15. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  16. Article
  17. Article
  18. Modulation of macrophage survival duringFrontiers in cellular and infection microbiology · 2026
    Review
  19. Genomic characterisation and antimicrobial resistance ofFrontiers in cellular and infection microbiology · 2026
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashish KumarDepartment of Biochemistry & Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA.
Somnath ChakravortyDepartment of Biochemistry & Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA.
Taihao YangDepartment of Biochemistry & Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA.
Thomas A RussoJacobs School of Medicine, University at Buffalo, Buffalo, New York, USA.ORCID 0000-0003-4566-7442
Salete M NewtonDepartment of Biochemistry & Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA.
Phillip E KlebbaDepartment of Biochemistry & Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA.ORCID 0000-0002-6979-3083

Funding

Development of a diagnostic test for hypervirulent Klebsiella pneumoniaeR21AI123558 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI RUSSO, THOMAS A · 2016 to 2017
$439k
Identification of genes essential for survival of hypervirulent Kleb. pneumoniaeR21AI088318 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI RUSSO, THOMAS A · 2011 to 2012
$436k
Identification of new or unrecognized virulence genes in hypervirulent Klebsiella pneumoniae and antivirulence genes in classical K. pneumoniae.R21AI141826 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI RUSSO, THOMAS A · 2020 to 2021
$432k
Determining the value of PBP 7/8 as an antimicrobial target for XDR-A. baumannniiI01BX004677 · VA · VA WESTERN NEW YORK HEALTHCARE SYSTEM · PI THOMAS A RUSSO · 2020 to 2026
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BLRD VA I01 BX004677NIAID NIH HHS R21 AI088318NIAID NIH HHS R21 AI123558NIAID NIH HHS R21 AI141826NIH HHS R21 AI123558-01 and 1R21AI141826-01A1The Department of Veterans Affairs VA Merit Review I01 BX004677-01
6 · The paper itself

Abstract

Microbes synthesize and secrete siderophores, that bind and solubilize precipitated or otherwise unavailable iron in their microenvironments. Gram (-) bacterial TonB-dependent outer membrane receptors capture the resulting ferric siderophores to begin the uptake process. From their similarity to IMPORTANCE: Both commensal and pathogenic bacteria produce small organic chelators, called siderophores, that avidly bind iron and increase its bioavailability.

Indexed as

IronKlebsiella pneumoniaeSiderophoresBacterial Outer Membrane ProteinsBacterial ProteinsBiological TransportCarrier ProteinsEnterobactinReceptors, Cell SurfaceBacterial Outer Membrane ProteinsBacterial ProteinsCarrier ProteinsEnterobactinenterobactin receptorIronReceptors, Cell SurfaceSiderophoresESKAPE pathogenferric enterobactinfluorescent sensorsiron transportKlebsiella pneumoniaesiderophore antibiotic conjugatessiderophoressite-directed mutagenesisTonB-dependent iron acquisition

Identifiers

PMID38591913
PMCPMC11112993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.