Evidence map›Paper›PMID 38591891›Full record

ReviewmSystems2024

More than two components: complexities in bacterial phosphosignaling.

Andrew Frando, Christoph Grundner

Abstract readReview
In one paragraph

Review in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Journal of bacteriology · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Exploration of Phosphoproteins inPathogens (Basel, Switzerland) · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew FrandoCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.ORCID 0000-0003-3476-1345
Christoph GrundnerCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.ORCID 0000-0003-0596-6798

Funding

Dual Targeting of Mtb Resistance MechanismsR01AI158159 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI GRUNDNER, CHRISTOPH · 2020 to 2024
$4.0M
INTERDISCIPLINARY PROGRAM IN BACTERIAL PATHOGENESIST32AI055396 · NIAID · UNIVERSITY OF WASHINGTON · PI FANG, FERRIC C · 2003 to 2019
$2.8M
Functional exploration of a deep Mycobacterium tuberculosis phosphoproteomeR01AI170914 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI Christoph Grundner · 2023 to 2026
$2.4M
Functional phosphosignaling in Mtb infectionR21AI153766 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI GRUNDNER, CHRISTOPH · 2020 to 2021
$491k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 5T32AI053396HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI170914, R01AI158159, R21AI153766NIAID NIH HHS R01 AI158159NIAID NIH HHS R01 AI170914NIAID NIH HHS R21 AI153766NIAID NIH HHS T32 AI055396
6 · The paper itself

Abstract

For over 40 years, the two-component systems (TCSs) have taken front and center in our thinking about the signaling mechanisms by which bacteria sense and respond to their environment. In contrast, phosphorylation on Ser/Thr and Tyr (

Indexed as

BacteriaBacterial ProteinsPhosphorylationProteomeSignal TransductionBacterial ProteinsProteomebacteriakinasesphosphoproteomicsphosphosignaling

Identifiers

PMID38591891
PMCPMC11097640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.