Evidence map›Paper›PMID 38591825›Full record

Observational studyJornal brasileiro de nefrologia2024

Percutaneous kidney biopsies in children: a 24-year review in a tertiary center in northern Portugal.

Patrícia Sousa, Catarina Brás, Catarina Menezes, Ramon Vizcaino, Teresa Costa, Maria Sameiro Faria, Conceição Mota

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Jornal brasileiro de nefrologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Patrícia SousaHospital Senhora da Oliveira, Serviço de Pediatria, Guimarães, Portugal.ORCID http://orcid.org/0000-0002-6809-036X
Catarina BrásHospital Professor Doutor Fernando Fonseca, Serviço de Nefrologia, Lisboa, Portugal.ORCID http://orcid.org/0000-0003-4643-2055
Catarina MenezesCentro Hospitalar Universitário de Santo António, Centro Materno-Infantil do Norte, Serviço de Pediatria, Porto, Portugal.ORCID http://orcid.org/0000-0001-7678-6693
Ramon VizcainoCentro Hospitalar Universitário de Santo António, Serviço de Anatomia Patológica, Porto, Portugal.
Teresa CostaCentro Hospitalar Universitário de Santo António, Centro Materno-Infantil do Norte, Unidade de Nefrologia Pediátrica, Serviço de Pediatria, Porto, Portugal.ORCID http://orcid.org/0000-0002-6478-4241
Maria Sameiro FariaCentro Hospitalar Universitário de Santo António, Centro Materno-Infantil do Norte, Unidade de Nefrologia Pediátrica, Serviço de Pediatria, Porto, Portugal.ORCID http://orcid.org/0000-0002-8061-9289
Conceição MotaCentro Hospitalar Universitário de Santo António, Centro Materno-Infantil do Norte, Unidade de Nefrologia Pediátrica, Serviço de Pediatria, Porto, Portugal.ORCID http://orcid.org/0000-0002-4741-0002
Weatherford College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPercutaneous kidney biopsy (KB) is crucial to the diagnosis and management of several renal pathologies. National data on native KB in pediatric patients are scarce. We aimed to review the demographic and clinical characteristics and histopathological patterns in children who underwent native percutaneous KB over 24 years.

methodsRetrospective observational study of patients undergoing native percutaneous KB in a pediatric nephrology unit between 1998 and 2021, comparing 3 periods: period 1 (1998-2005), period 2 (2006-2013), and period 3 (2014-2021).

resultsWe found that 228 KB were performed, 78 (34.2%) in period 1, 91 (39.9%) in period 2, and 59 (25.9%) in period 3. The median age at KB was 11 (7-14) years. The main indications for KB were nephrotic syndrome (NS) (42.9%), hematuria and/or non-nephrotic proteinuria (35.5%), and acute kidney injury (13.2%). Primary glomerulopathies were more frequent (67.1%), particularly minimal change disease (MCD) (25.4%), IgA nephropathy (12.7%), and mesangioproliferative glomerulonephritis (GN) (8.8%). Of the secondary glomerulopathies, lupus nephritis (LN) was the most prevalent (11.8%). In group 1, hematuria and/or non-nephrotic proteinuria were the main reasons for KB, as opposed to NS in groups 2 and 3 (p < 0.01). LN showed an increasing trend (period 1-3: 2.6%-5.3%) and focal segmental glomerular sclerosis (FSGS) showed a slight decreasing trend (period 1-3: 3.1%-1.8%), without statistical significance.

conclusionsThe main indication for KB was NS, which increased over time, justifying the finding of MCD as main histological diagnosis. LN showed an increase in incidence over time, while FSGS cases did not increase.

Indexed as

Glomerulonephritis, IGAGlomerulosclerosis, Focal SegmentalKidney DiseasesLupus NephritisNephrosis, LipoidNephrotic SyndromeAdolescentBiopsyChildHematuriaHumansKidneyPortugalProteinuriaRetrospective Studies

Identifiers

PMID38591825
PMCPMC11287898
OpenAlexW4394570769

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.