ArticleWorkplace health & safety2024
Association Between Acute Kidney Injury Hospital Visits and Environmental Heat Stress at a Nicaraguan Sugarcane Plantation.
Article in Workplace health & safety, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Extreme weather effects on health services and communities in low and lower-middle income countries: a thematic systematic review.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2026Pooled it
- Pediatric kidney health outcomes in communities impacted by chronic kidney disease of unknown etiology (CKDu): a systematic review.Pediatric nephrology (Berlin, Germany) · 2026Pooled it
- Hydrating with a higher-fructose sport drink does not worsen acute kidney injury risk during simulated work-related heat stress.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Trial
- Association between ambient temperature and acute kidney injury: a nationwide space-time-stratified case-crossover study in Japan.Journal of exposure science & environmental epidemiology · 2026Article
- Epidemiology, mechanisms and clinical implications of heat-related kidney disease.Nature reviews. Nephrology · 2026Review
- Symptoms of heat stress predict changes in serum creatinine among rural patients with chronic kidney disease during heatwave conditions in Northern India.BMC nephrology · 2025Observational
- Rest, shade, hydration and hygiene for the prevention of kidney injuries and inflammation in a Nicaraguan sugarcane worker cohort.Occupational and environmental medicine · 2025Article
- Hyperthermia Predicts Cross-Shift Acute Kidney Injury Risk in Construction Workers.Kidney international reports · 2025Article
- Work and work exposures in sugarcane farming in Eswatini, Southern Africa.International archives of occupational and environmental health · 2025Article
- Occupational exposure to respirable and inhalable dust and its components in a Nicaraguan sugarcane plantation.Occupational and environmental medicine · 2025Article
- Heat-Related Kidney Injury Precedes Estimated GFR Decline in Workers at Risk of CKD.Kidney international reports · 2025Article
- Using environmental and exercise physiology to address gender inequalities in climate change and occupational health research.Experimental physiology · 2025Review
- Economic Analysis of a Rest-Shade-Hydration-Sanitation Program at a Nicaraguan Sugar Mill.Annals of global health · 2025Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMesoamerican sugarcane cutters are at a high risk of chronic kidney disease of non-traditional origin, a disease likely linked to heat-related acute kidney injury (AKI). Studies in general populations have described a positive association between high environmental temperatures and clinically assessed kidney outcomes, but there are no studies in occupational settings.
methodWe accessed routine records of clinically diagnosed AKI (AKI-CD) and wet bulb globe temperatures (WBGT) at a large Nicaraguan sugarcane plantation and modeled the relationship between these using negative binomial regression. A rest-shade-hydration intervention was gradually enhanced during the study period, and efforts were made to increase the referral of workers with suspected AKI to healthcare.
resultsEach 1°C WBGT was associated with an 18% (95% confidence interval [CI]: [4, 33%]) higher AKI-CD rate on the same day and a 14% (95% CI [-5, 37%]) higher rate over a week. AKI-CD rates and severity, and time between symptoms onset and diagnosis decreased during the study period, that is, with increasing rest-shade-hydration intervention. Symptoms and biochemical signs of systemic inflammation were common among AKI-CD cases. DISCUSSION: Occupational heat stress, resulting from heavy work in environmental heat, was associated with a higher rate of clinically diagnosed AKI in a population at risk of CKDnt. Promoting rest-shade-hydration may have contributed to reducing AKI rates during the study period. Occupational health and safety personnel have key roles to play in enforcing rest, shade, and hydration practices, referring workers with suspected AKI to healthcare as well as collecting and analyzing the data needed to support workplace heat stress interventions.
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