Evidence map›Paper›PMID 38591039›Full record

ArticleFrontiers in microbiology2024

Integrated 16S rRNA sequencing and metagenomics insights into microbial dysbiosis and distinct virulence factors in inflammatory bowel disease.

Haijing Wang, Yuanjun Wang, Libin Yang, Jiawen Feng, Shou Tian, Lingyan Chen, Wei Huang, Jia Liu, Xiaojin Wang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  10. Extracellular vesicles from pasteurizedFrontiers in microbiology · 2026
    Article
  11. Review
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  13. Article
  14. Engineered Tissue Models to Decode Host-Microbiota Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Haijing Wang *Medical College of Qinghai University, Xining, China.
Yuanjun Wang *Medical College of Qinghai University, Xining, China.
Libin YangNingxia Hui Autonomous Region People's Hospital, Yinchuan, China.
Jiawen FengMedical College of Qinghai University, Xining, China.
Shou TianMedical College of Qinghai University, Xining, China.
Lingyan ChenQinghai Provincial Traditional Chinese Medicine Hospital, Xining, China.
Wei HuangQinghai Provincial Traditional Chinese Medicine Hospital, Xining, China.
Jia LiuQinghai Provincial Traditional Chinese Medicine Hospital, Xining, China.
Xiaojin WangMedical College of Qinghai University, Xining, China.
Qinghai Provincial Peoples Hospital · CNQinghai University · CNNingxia Hui Autonomous Region Peoples Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The escalation of urbanization correlates with rising rates of inflammatory bowel disease (IBD), necessitating research into new etiological factors. This study aims to elucidate the gut microbiota profiles in IBD patients and compare them with healthy controls in a western city of China. Methods: We conducted a multicenter case-control study from the end of 2020, using 16S rRNA gene sequencing ( Results: Our results demonstrated a significant enrichment of the phylum Proteobacteria, particularly the genus Discussion: The findings suggest that oxidative stress may play a pivotal role in the pathology of IBD. This study contributes to the growing dialogue about the impact of gut microbiota on the development of IBD and its variations across different geographies, highlighting potential avenues for further research.

Indexed as

16S rRNAcase-control studyCrohn's diseaseinflammatory bowel diseasemetagenomeulcerative colitis

Identifiers

PMID38591039
PMCPMC10999624
OpenAlexW4393155721

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.