Evidence map›Paper›PMID 38591012›Full record

ArticleiScience2024

Neurophysiological effective network connectivity supports a threshold-dependent management of dynamic working memory gating.

Julia Elmers, Shijing Yu, Nasibeh Talebi, Astrid Prochnow, Christian Beste

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  11. Directed Neural Network Dynamics in Sensorimotor Integration: Divergent Roles of Frontal Theta Band Activity Depending on Age.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia ElmersCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany.
Shijing YuCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany.
Nasibeh TalebiCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany.
Astrid ProchnowCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany.
Christian BesteCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To facilitate goal-directed actions, effective management of working memory (WM) is crucial, involving a hypothesized WM "gating mechanism." We investigate the underlying neural basis through behavioral modeling and connectivity assessments between neuroanatomical regions linked to theta, alpha, and beta frequency bands. We found opposing, threshold-dependent mechanisms governing WM gate opening and closing. Directed beta band connectivity in the parieto-frontal and parahippocampal-occipital networks was crucial for threshold-dependent WM gating dynamics. Fronto-parahippocampal connectivity in the theta band was also notable for both gating processes, although weaker than that in the beta band. Distinct roles for theta, beta, and alpha bands emerge in maintaining information in WM and shielding against interference, whereby alpha band activity likely acts as a "gatekeeper" supporting processes reflected by beta and theta band activity. The study shows that the decision criterion for WM gate opening/closing relies on concerted interplay within neuroanatomical networks defined by beta and theta band activities.

Indexed as

Cognitive neuroscienceNeuroscience

Identifiers

PMID38591012
PMCPMC11000016

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.