Evidence map›Paper›PMID 38590738›Full record

ArticleWorld neurosurgery: X2024

Andexanet alfa therapy showed No increased rate of thromboembolic events in spontaneous intracranial hemorrhage patients: A multicenter electronic health record study.

John Vellek, Omar H Tarawneh, Syed Faraz Kazim, Oluwafemi P Owodunni, Sophia Arbuiso, Smit Shah, Alis J Dicpinigaitis, Meic H Schmidt, Rohini G McKee, Richard Miskimins and 2 more

Open access · goldAbstract read
In one paragraph

Article in World neurosurgery: X, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

John VellekSchool of Medicine, New York Medical College, Valhalla, NY, 10595, United States.
Omar H TarawnehSchool of Medicine, New York Medical College, Valhalla, NY, 10595, United States.
Syed Faraz KazimDepartment of Neurosurgery, University of New Mexico Hospital (UNMH), Albuquerque, NM, 87131, United States.
Oluwafemi P OwodunniDepartment of Neurosurgery, University of New Mexico Hospital (UNMH), Albuquerque, NM, 87131, United States.
Sophia ArbuisoSchool of Medicine, New York Medical College, Valhalla, NY, 10595, United States.
Smit ShahPRISMA Health Richland/University of South Carolina School of Medicine, 1 Medical Park, Suite 230, Columbia, SC, 29203, United States.
Alis J DicpinigaitisSchool of Medicine, New York Medical College, Valhalla, NY, 10595, United States.
Meic H SchmidtDepartment of Neurosurgery, University of New Mexico Hospital (UNMH), Albuquerque, NM, 87131, United States.
Rohini G McKeeDepartment of Surgery, University of New Mexico, Albuquerque, NM, 87106, United States.
Richard MiskiminsDepartment of Surgery, University of New Mexico, Albuquerque, NM, 87106, United States.
Fawaz Al-MuftiDepartment of Neurosurgery, Westchester Medical Center/New York Medical College, Valhalla, NY, 10595, United States.
Christian A BowersBowers Neurosurgical Frailty and Outcomes Data Science Lab, Sandy, UT, United States.
New York Medical College · USUniversity of New Mexico Hospital · USUniversity of New Mexico · USUniversity of South Carolina · USWestchester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•Intracranial hemorrhage accounts for two out of every three major intracranial hemorrhages.•Systemic anticoagulation is routinely prescribed for prevention of cerebrovascular accidents.•The FDA approved Andexanet alfa to treat life-threatening bleeding.•Andexanet alfa relationship to outcomes requires further investigation.

Indexed as

Andexanet AlfaAnticoagulationIntracranial HemorrhageThromboembolism

Identifiers

PMID38590738
PMCPMC10999854
OpenAlexW4393236878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.