Evidence map›Paper›PMID 38590608›Full record

ArticleJournal of immunology research2024

Circulating Immune Landscape Profiling in Psoriasis Vulgaris and Psoriatic Arthritis by Mass Cytometry.

Xudong Sang, Tian Gan, Gai Ge, Dan Li, Youming Mei, Chun Pan, Siyu Long, Bibo Xie, Xiaobing Yu, Zhiming Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Xudong SangZhejiang Institute of Dermatology, Deqing, China.
Tian GanInstitute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.ORCID https://orcid.org/0009-0001-6420-0082
Gai GeInstitute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Dan LiZhejiang Institute of Dermatology, Deqing, China.
Youming MeiInstitute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Chun PanInstitute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Siyu LongInstitute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Bibo XieZhejiang Institute of Dermatology, Deqing, China.
Xiaobing YuZhejiang Institute of Dermatology, Deqing, China.
Zhiming ChenInstitute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.ORCID https://orcid.org/0000-0002-3097-0126
Hongsheng WangInstitute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.ORCID https://orcid.org/0000-0001-5725-5053
Chinese Academy of Medical Sciences & Peking Union Medical College · CNYueqing People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Psoriasis, a systemic disorder mediated by the immune system, can appear on the skin, joints, or both. Individuals with cutaneous psoriasis (PsC) have an elevated risk of developing psoriatic arthritis (PsA) during their lifetime. Despite this known association, the cellular and molecular mechanisms underlying this progression remain unclear. Methods: We performed high-dimensional, in-depth immunophenotyping of peripheral blood mononuclear cells (PBMCs) in patients with PsA and psoriasis vulgaris (PsV) by mass cytometry. Blood samples were collected before and after therapy for a longitudinal study. Then three sets of comparisons were made here: active PsA Results: Marked differences were observed in multiple lymphocyte subsets of PsA related to PsV, with expansion of CD4 Conclusion: In the circulation of PsA patients, the T

Indexed as

Arthritis, PsoriaticPsoriasisCD28 AntigensHumansLeukocytes, MononuclearLongitudinal StudiesCD28 Antigens

Identifiers

PMID38590608
PMCPMC11001477
OpenAlexW4393374364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.