Evidence map›Paper›PMID 38590603›Full record

ArticleMateria socio-medica2024

Association of Anti-Ro/SSA and Anti-La/SSB Autoantibodies With Pregnancy Outcome in the General Population.

Georgios Dragoutsos, Christina Tsiggalou, Efthymios Oikonomou, Anastasia Bothou, Grigorios Trypsiannis, Konstantinos Nikolettos, Christos Damaskos, Nikolaos Garmpis, Dimitrios Kyriakou, Theopi Nalbanti and 3 more

Open access · greenAbstract read
In one paragraph

Article in Materia socio-medica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Georgios DragoutsosDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Christina TsiggalouDepartment of Medical Micobiology-Immunology Laboratory of Hygiene and Environmental Protection Democritus University of Thrace, Greece.
Efthymios OikonomouDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Anastasia BothouDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Grigorios TrypsiannisDepartment of Medical Statistics, Democritus University of Thrace, Greece.
Konstantinos NikolettosDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Christos DamaskosExperimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Greece and Renal Transplantation Unit, Laiko General Hospital, Athens, Greece.
Nikolaos GarmpisLaboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Greece.
Dimitrios KyriakouDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Theopi NalbantiDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Georgios IatrakisDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Nikolaos NikolettosDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Panagiotis TsikourasDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Democritus University of Thrace · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autoimmune diseases encompass a diverse array of disorders that disturb the optimal functioning of the immune system, which is to eliminate the 'foreign or/and dangerous' to mistakenly target the body's own tissues. Objective: The aim of this research is to evaluate the most effective approach to managing autoimmune diseases within the framework of pregnancy. Methods: The exact causes and etiologies of these diseases are multifactorial and mostly still unclear. Ro/SSA autoantibodies and La/SSB, could be found in Sjögren's disease (SJ), systemic lupus (SLE) and other autoimmune disorders. Smoking, stress, UV exposure, vitamin D deficiency, and other genetic and environmental factors have been identified as risk factors for rheumatic diseases. Results: Over the years, an ever-increasing incidence of these diseases has been observed in the general population, with the female sex being at increased risk for their occurrence. This fact raises the question of what should be the management of these pathological entities during pregnancy. Taking into account the very significant impact on the quality of paitients'daily life and the seemingly augmented prevalence of autoimmune diseases, as well as their preference in the female population, the reasonable question arises as to what should be the optimal management of these diseases in the context of pregnancy. Conclusion: Given the limited data of the global medical community regarding the etiological factors and mechanisms that trigger the onset of rheumatic diseases, the management of pregnant women is a complex conundrum that health professionals are challenged to face and solve.

Indexed as

anti-La/SSB autoantibodiesanti-Ro/SSAgeneral populationpregnancy outcome

Identifiers

PMID38590603
PMCPMC10999136
OpenAlexW4392635017

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.