Evidence map›Paper›PMID 38590432›Full record

ArticleFrontiers in molecular neuroscience2024

Generation of contractile forces by three-dimensional bundled axonal tracts in micro-tissue engineered neural networks.

Dimple Chouhan, Wisberty J Gordián Vélez, Laura A Struzyna, Dayo O Adewole, Erin R Cullen, Justin C Burrell, John C O'Donnell, D Kacy Cullen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dimple Chouhan *Department of Neurosurgery, Center for Brain Injury and Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Wisberty J Gordián Vélez *Department of Neurosurgery, Center for Brain Injury and Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Laura A StruzynaDepartment of Neurosurgery, Center for Brain Injury and Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Dayo O AdewoleDepartment of Neurosurgery, Center for Brain Injury and Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Erin R CullenDepartment of Neurosurgery, Center for Brain Injury and Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Justin C BurrellDepartment of Neurosurgery, Center for Brain Injury and Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
John C O'DonnellDepartment of Neurosurgery, Center for Brain Injury and Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
D Kacy CullenDepartment of Neurosurgery, Center for Brain Injury and Repair, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Philadelphia VA Medical Center · USUniversity of Pennsylvania · US

Funding

NRSA Training CoreTL1TR001880 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI MEAGHER, EMMA ANNE · 2016 to 2025
$10.0M
Training Program in Neuroengineering and MedicineT32NS091006 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Brian Litt · 2015 to 2026
$4.1M
Tissue Engineered Rostral Migratory Stream for Directed Neuronal ReplacementR01NS117757 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI CULLEN, DANIEL KACY · 2021 to 2025
$2.9M
Tissue Engineered Nigrostriatal Pathway for Anatomical Tract Reconstruction in Parkinson's DiseaseR01NS127895 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Daniel Kacy Cullen · 2023 to 2026
$2.3M
Advanced Training at the Interface of Engineering and Oral-Craniofacial SciencesT90DE030854 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI Hyun Koo, Kathleen J Stebe · 2021 to 2026
$1.4M
Transplantable Micro-Tissue Engineered Neural Networks to Restore the Nigrostriatal Pathway in Parkinson's DiseaseI01BX003748 · VA · PHILADELPHIA VA MEDICAL CENTER · PI CULLEN, DANIEL KACY · 2017 to 2022
–
Translational Modeling of Brain Injury Rehabilitation to Maximize Recovery.IK2RX003376 · VA · PHILADELPHIA VA MEDICAL CENTER · PI John Charles O'Donnell · 2021 to 2026
–
BLRD VA I01 BX003748NCATS NIH HHS TL1 TR001880NIDCR NIH HHS T90 DE030854NINDS NIH HHS R01 NS117757NINDS NIH HHS R01 NS127895NINDS NIH HHS T32 NS091006RRD VA IK2 RX003376
6 · The paper itself

Abstract

Axonal extension and retraction are ongoing processes that occur throughout all developmental stages of an organism. The ability of axons to produce mechanical forces internally and respond to externally generated forces is crucial for nervous system development, maintenance, and plasticity. Such axonal mechanobiological phenomena have typically been evaluated

Indexed as

axon contractionaxon mechanicsaxon tractscortical neuronsmechanical forces

Identifiers

PMID38590432
PMCPMC10999686
OpenAlexW4393152898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.