Evidence map›Paper›PMID 38590406›Full record

ArticleAmerican journal of cancer research2024

Novel chromium (III)-based compound for inhibition of oxaliplatin-resistant colorectal cancer progression.

Ming-Cheng Chen, Hema Sri Devi, Hsueh-Fa Pien, Shina Fong-Mei Wen, Jenn-Line Sheu, Bruce Chi-Kang Tsai, Chih-Yang Huang, Yu-Jung Lin

Open access · bronzeAbstract read
In one paragraph

Article in American journal of cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ming-Cheng ChenDivision of Colorectal Surgery, Department of Surgery, Taichung Veterans General Hospital Taichung, Taiwan.
Hema Sri DeviCardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Hualien, Taiwan.
Hsueh-Fa PienTOMA Biotechnology Co., Ltd. Taipei, Taiwan.
Shina Fong-Mei WenTOMA Biotechnology Co., Ltd. Taipei, Taiwan.
Jenn-Line SheuTOMA Biotechnology Co., Ltd. Taipei, Taiwan.
Bruce Chi-Kang TsaiCardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Hualien, Taiwan.
Chih-Yang HuangCardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Hualien, Taiwan.
Yu-Jung LinCardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Hualien, Taiwan.
Taichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) ranks as the third leading cause of cancer-related mortality worldwide. The current standard of care includes systemic chemotherapy with cytotoxic agents, offering palliative relief for severe CRC cases and serving as the primary therapy for metastatic recurrence. However, the development of chemoresistance poses a substantial obstacle in the realm of chemotherapy. This study delved into the potential of a novel chromium (III)-based compound, hexaacetotetraaquadihydroxochromium (III) diiron (III) nitrate, for CRC treatment. The therapeutic promise of this innovative chromium (III)-based compound was explored by utilizing LoVo colon cancer cells and an

Indexed as

apoptosischromium (III)-based compoundcolorectal cancerHexaacetotetraaquadihydroxochromium (III) diiron (III) nitrateoxaliplatin-drug resistant

Identifiers

PMID38590406
PMCPMC10998745
OpenAlexW4394001045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.