Evidence map›Paper›PMID 38590326›Full record

ArticleLancet regional health. Americas2024

Spectrum of prevalent cardiovascular diseases in urban Port-au-Prince, Haiti: a population-based cross-sectional study.

Lily D Yan, Rodney Sufra, Reichling St Sauveur, Marie Christine Jean-Pierre, Alexandra Apollon, Rodolphe Malebranche, Michel Théard, Gerard Pierre, Jessy Dévieux, Jennifer Lau and 18 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Lancet regional health. Americas, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03892265 (A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03892265 active not recruitingnot on this map

A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti

TypeobservationalSponsorWeill Medical College of Cornell UniversityRan2019 to 2028Enrolled3,005ConditionsHypertension, Diabetes, Obesity, Kidney DiseasesArmsObservational Study
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 7 institutions in 2 countries.

Lily D YanCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Rodney SufraHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Reichling St SauveurHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Marie Christine Jean-PierreHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Alexandra ApollonHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Rodolphe MalebrancheCollège Haïtien de Cardiologie, Port-au-Prince, Haiti.
Michel ThéardCollège Haïtien de Cardiologie, Port-au-Prince, Haiti.
Gerard PierreCollège Haïtien de Cardiologie, Port-au-Prince, Haiti.
Jessy DévieuxDepartment of Health Promotion and Disease Prevention, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA.
Jennifer LauDivision of General Internal Medicine, Weill Cornell Medicine, NYC, NY, USA.
Nour MourraCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Nicholas L S RobertsDivision of General Internal Medicine, Weill Cornell Medicine, NYC, NY, USA.
Rehana RasulCity University of New York Institute for Implementation Science in Population Health, New York, NY, USA.
Denis NashCity University of New York Institute for Implementation Science in Population Health, New York, NY, USA.
Altaf M PirmohamedDivision of Cardiology, Weill Cornell Medicine, NYC, NY, USA.
Richard B DevereuxDivision of Cardiology, Weill Cornell Medicine, NYC, NY, USA.
Myung Hee LeeCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Gene F KwanDivision of Cardiology, Boston University School of Medicine, Boston, MA, USA.
Monika M SaffordDivision of General Internal Medicine, Weill Cornell Medicine, NYC, NY, USA.
Lauré AdrienDirector General, Ministry of Public Health and Population, Haiti.
Jean Patrick AlfredDirector of Studies and Programming, Ministry of Public Health and Population, Haiti.
Marie DeschampsHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Patrice SevereHaitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Daniel W FitzgeraldCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Jean W PapeCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Vanessa RouzierCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Margaret L McNairyCenter for Global Health, Weill Cornell Medicine, NYC, NY, USA.
Haiti Cardiovascular Disease Cohort study team
Cornell University · USGheskio Centers · HTCity University of New York · USBoston University · USFlorida International University · USMinistry of Public Works Transportation and Communications · HTUniversity of Haiti · HT

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep DisordersR01HL143788 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Margaret Leighton McNairy · 2018 to 2026
$8.9M
Cardiovascular Disease Research Training Program in HaitiD43TW011972 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI Margaret Leighton McNairy, JEAN WILLIAM PAPE · 2021 to 2026
$1.4M
Identifying facilitators and barriers to heart failure care in Haiti to adapt a community-based interventionK23HL140133 · NHLBI · BOSTON MEDICAL CENTER · PI KWAN, GENE FAZIL · 2019 to 2022
$663k
Global Health Research and Training in Cardiovascular DiseaseK24HL163393 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Margaret Leighton McNairy · 2022 to 2026
$604k
Simulator-Based simplified Focused Cardiac Ultrasound (sFoCUS) Training in HaitiR21TW012165 · FIC · BOSTON MEDICAL CENTER · PI KWAN, GENE FAZIL · 2022 to 2023
$478k
FIC NIH HHS D43 TW011972FIC NIH HHS R21 TW012165NCATS NIH HHS UL1 TR002384NHLBI NIH HHS K23 HL140133NHLBI NIH HHS K24 HL163393NHLBI NIH HHS R01 HL143788NIAID NIH HHS U01 AI096299
6 · The paper itself

Abstract

Background: Eighty percent of global cardiovascular disease (CVD) is projected to occur in low- and middle -income countries (LMICs), yet local epidemiological data are scarce. We provide the first population-based, adjudicated CVD prevalence estimates in Port-au-Prince, Haiti to describe the spectrum of heart disease and investigate associated risk factors. Methods: Demographic, medical history, clinical, imaging and laboratory data were collected among adults recruited using multistage random sampling from 2019 to 2021. Prevalent CVD (heart failure, stroke, ischemic disease) were adjudicated using epidemiological criteria similar to international cohorts. Multivariable Poisson regressions assessed relationships between risk factors and prevalent CVD. Findings: Among 3003 participants, median age was 40 years, 58.1% were female, 70.2% reported income <1 USD/day, and all identified as Black Haitian. CVD age-adjusted prevalence was 14.7% (95% CI 13.3%, 16.5%), including heart failure (11.9% [95% CI 10.5%, 13.5%]), stroke (2.4% [95% CI 1.9%, 3.3%]), angina (2.1% [95% CI 1.6%, 2.9%]), myocardial infarction (1.0% [95% CI 0.6%, 1.8%]), and transient ischemic attack (0.4% [95% CI 0.2%, 1.0%]). Among participants with heart failure, median age was 57 years and 68.5% of cases were among women. The most common subtype was heart failure with preserved ejection fraction (80.4%). Heart failure was associated with hypertension, obesity, chronic kidney disease, depression, and stress. Interpretation: Early-onset heart failure prevalence is alarmingly high in urban Haiti and challenge modelling assumptions that ischemic heart disease and stroke dominate CVDs in LMICs. These data underscore the importance of local population-based epidemiologic data within LMICs to expedite the selection and implementation of evidence-based cardiovascular health policies targeting each country's spectrum of heart disease. Funding: This study was funded by NIH grants R01HL143788, D43TW011972, and K24HL163393, clinicaltrials.govNCT03892265.

Indexed as

Cardiovascular diseaseCohortGlobal healthHaitiHeart failureHypertensionMyocardial infarctionStroke

Identifiers

PMID38590326
PMCPMC11000196
OpenAlexW4393963186

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.