Evidence map›Paper›PMID 38589956›Full record

ReviewStem cell research & therapy2024

Utilizing bioprinting to engineer spatially organized tissues from the bottom-up.

Yichen Zhan, Wenbin Jiang, Zhirong Liu, Zhenxing Wang, Ke Guo, Jiaming Sun

Abstract readReview
In one paragraph

Review in Stem cell research & therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Critical Systematic Review of 3D Bioprinting in Biomedicine.International journal of molecular sciences · 2025
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Organoids and tissue/organ chips.Stem cell research & therapy · 2024
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yichen Zhan *Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Wenbin Jiang *Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Zhirong LiuDepartment of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. liuzhirong1818@126.com.
Zhenxing WangDepartment of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. benjamin.wzx@163.com.ORCID 0000-0002-2436-0372
Ke GuoDepartment of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. gkiseric@126.com.
Jiaming SunDepartment of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. sunjm1592@sina.com.

Funding

National Key Research and Development Program of China 2019YFA0110500National Natural Science Foundation of China 81701922National Natural Science Foundation of China 82020108020National Natural Science Foundation of China 82072198National Natural Science Foundation of China 82322046Natural Science Foundation of Hubei Province 2023020201020502Natural Science Foundation of Hubei Province 2023KQHM01Natural Science Foundation of Hubei Province 2023-XHJS-004Natural Science Foundation of Hubei Province 2023-XHJS-015Natural Science Foundation of Hubei Province WJ2021Z008
6 · The paper itself

Abstract

In response to the growing demand for organ substitutes, tissue engineering has evolved significantly. However, it is still challenging to create functional tissues and organs. Tissue engineering from the 'bottom-up' is promising on solving this problem due to its ability to construct tissues with physiological complexity. The workflow of this strategy involves two key steps: the creation of building blocks, and the subsequent assembly. There are many techniques developed for the two pivotal steps. Notably, bioprinting is versatile among these techniques and has been widely used in research. With its high level of automation, bioprinting has great capacity in engineering tissues with precision and holds promise to construct multi-material tissues. In this review, we summarize the techniques applied in fabrication and assembly of building blocks. We elaborate mechanisms and applications of bioprinting, particularly in the 'bottom-up' strategy. We state our perspectives on future trends of bottom-up tissue engineering, hoping to provide useful reference for researchers in this field.

Indexed as

BioprintingTissue EngineeringTissue ScaffoldsAssemblyBioprintingBottom-upBuilding blocksTissue engineering

Identifiers

PMID38589956
PMCPMC11003108

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.