Evidence map›Paper›PMID 38589795›Full record

SynthesisBMC infectious diseases2024

A systematic review on antibiotic therapy of cutaneous bacillary angiomatosis not related to major immunocompromising conditions: from pathogenesis to treatment.

Salvatore Rotundo, Maria Teresa Tassone, Nadia Marascio, Helen Linda Morrone, Simona Gigliotti, Angela Quirino, Alessandro Russo, Giovanni Matera, Enrico Maria Trecarichi, Carlo Torti

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Salvatore RotundoDipartimento di Scienze Mediche e Chirurgiche, Università "Magna Graecia", Catanzaro, Italy.
Maria Teresa TassoneDipartimento di Scienze Mediche e Chirurgiche, Università "Magna Graecia", Catanzaro, Italy.
Nadia MarascioDipartimento di Scienze della Vita, Unità Operativa Complessa di Microbiologica Clinica, Università "Magna Graecia", Catanzaro, Italy.
Helen Linda MorroneDipartimento di Scienze Mediche e Chirurgiche, Università "Magna Graecia", Catanzaro, Italy.
Simona GigliottiDipartimento di Scienze della Vita, Unità Operativa Complessa di Microbiologica Clinica, Università "Magna Graecia", Catanzaro, Italy.
Angela QuirinoDipartimento di Scienze della Vita, Unità Operativa Complessa di Microbiologica Clinica, Università "Magna Graecia", Catanzaro, Italy.
Alessandro RussoDipartimento di Scienze Mediche e Chirurgiche, Università "Magna Graecia", Catanzaro, Italy.
Giovanni MateraDipartimento di Scienze della Vita, Unità Operativa Complessa di Microbiologica Clinica, Università "Magna Graecia", Catanzaro, Italy.
Enrico Maria TrecarichiDipartimento di Scienze Mediche e Chirurgiche, Università "Magna Graecia", Catanzaro, Italy.
Carlo TortiDipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy. carlo.torti@unicatt.it.
Magna Graecia University · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCutaneous bacillary angiomatosis (cBA) is a vascular proliferative disorder due to Bartonella spp. that mostly affects people living with HIV (PLWH), transplanted patients and those taking immunosuppressive drugs. Since cBA is mostly related to these major immunocompromising conditions (i.e., T-cell count impairment), it is considered rare in relatively immunocompetent patients and could be underdiagnosed in them. Moreover, antimicrobial treatment in this population has not been previously investigated.

methodsWe searched the databases PubMed, Google Scholar, Scopus, OpenAIRE and ScienceDirect by screening articles whose title included the keywords "bacillary" AND "angiomatosis" and included case reports about patients not suffering from major immunocompromising conditions to provide insights about antibiotic treatments and their duration.

resultsTwenty-two cases of cBA not related to major immunocompromising conditions were retrieved. Antibiotic treatment duration was shorter in patients with single cBA lesion than in patients with multiple lesions, including in most cases macrolides and tetracyclines.

conclusionscBA is an emerging manifestation of Bartonella spp. infection in people not suffering from major immunocompromising conditions. Until evidence-based guidelines are available, molecular tests together with severity and extension of the disease can be useful to personalize the type of treatment and its duration.

Indexed as

Angiomatosis, BacillaryAnti-Bacterial AgentsAdultAgedBartonellaFemaleHumansImmunocompromised HostMaleMiddle AgedAnti-Bacterial AgentsAntibioticBacillary angiomatosisBartonellaEmerging diseaseOne healthPCR

Identifiers

PMID38589795
PMCPMC11000314
OpenAlexW4394572257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.