Evidence map›Paper›PMID 38589672›Full record

Observational studyGeroScience2024

The association between blood biological age at rehabilitation admission and physical activity during rehabilitation in geriatric inpatients: RESORT.

Jessica K Lu, Lihuan Guan, Weilan Wang, Anna G M Rojer, Fedor Galkin, Jorming Goh, Andrea B Maier

Abstract readObservational Study
In one paragraph

Observational study in GeroScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jessica K LuCentre for Healthy Longevity, National University Health System, Singapore, Singapore.
Lihuan GuanCentre for Healthy Longevity, National University Health System, Singapore, Singapore.
Weilan WangCentre for Healthy Longevity, National University Health System, Singapore, Singapore.
Anna G M RojerDepartment of Human Movement Sciences, @AgeAmsterdam, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Van Der Boechorstsraat 7, 1081 BT, Amsterdam, The Netherlands.
Fedor GalkinDeep Longevity, Hong Kong, China.
Jorming GohCentre for Healthy Longevity, National University Health System, Singapore, Singapore.
Andrea B MaierCentre for Healthy Longevity, National University Health System, Singapore, Singapore. a.b.maier@vu.nl.ORCID 0000-0001-7206-1724

Funding

European Union's Horizon 2020 program 675003European Union's Horizon 2020 Program 689238
6 · The paper itself

Abstract

Geriatric rehabilitation inpatients have high levels of sedentary behaviour (SB) and low levels of physical activity (PA). Biological age predicted by blood biomarkers is indicative of adverse outcomes. The objective was to determine the association between blood biological age at rehabilitation admission and levels of SB and PA during rehabilitation in geriatric inpatients. Inpatients admitted to geriatric rehabilitation wards at the Royal Melbourne Hospital (Melbourne, Australia) from October 22, 2019, to March 29, 2020, in the REStORing health of acute unwell adulTs (RESORT) observational cohort were included. Blood biological age was predicted using SenoClock-BloodAge, a hematological ageing clock. Patients wore an inertial sensor to measure SB and PA. Logistic regression analyses were conducted. A total of 111 patients (57.7% female) with mean age 83.3 ± 7.5 years were included in the analysis. The mean blood biological age was 82.7 ± 8.4 years. Patients with 1-year higher blood biological age had higher odds of having high SB measured as non-upright time greater than 23 h/day (odds ratio (OR): 1.050, 95% confidence interval (CI): 1.000-1.102). Individuals having 1-year higher age deviation trended towards lower odds of having high levels of PA measured as stepping time greater than 7.4 min/day (OR: 0.916, CI: 0.836-1.005) and as greater than 19.5 sit-to-stand transitions/day (OR: 0.915, CI: 0.836-1.002). In conclusion, higher biological age was associated with higher levels of SB and trended towards lower PA. Incorporating blood biological age could facilitate resource allocation and the development of more tailored rehabilitation plans.

Indexed as

Age FactorsExerciseGeriatric AssessmentRehabilitationSedentary BehaviorAgedAged, 80 and overAustraliaBiomarkersFemaleHospitalizationHumansInpatientsMaleBiomarkersAccelerometryAgeingPhysical activityRehabilitationSedentary behaviour

Identifiers

PMID38589672
PMCPMC11336003

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.