Evidence map›Paper›PMID 38589431›Full record

ArticleScientific reports2024

Identification of 6-methyladenosine sites using novel feature encoding methods and ensemble models.

Nashwan Alromema, Muhammad Taseer Suleman, Sharaf J Malebary, Amir Ahmed, Bandar Ali Mohammed Al-Rami Al-Ghamdi, Yaser Daanial Khan

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nashwan AlromemaDepartment of Computer Science, Faculty of Computing and Information Technology-Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.
Muhammad Taseer SulemanDepartment of Computer Science, School of Systems and Technology, University of Management and Technology, Lahore, 54770, Pakistan. s2018288002@umt.edu.pk.
Sharaf J MalebaryDepartment of Information Technology, Faculty of Computing and Information Technology-Rabigh, King Abdulaziz University, P.O. Box 344, 21911, Rabigh, Saudi Arabia.
Amir AhmedDepartment of Information Systems and Security, College of Information Technology, United Arab Emirates University, Alain, United Arab Emirates.
Bandar Ali Mohammed Al-Rami Al-GhamdiFaculty of Computer Studies, Arab Open University, Riyadh, 11681, Saudi Arabia.
Yaser Daanial KhanDepartment of Computer Science, School of Systems and Technology, University of Management and Technology, Lahore, 54770, Pakistan.

Funding

Ministry of Education and King Abdulaziz University, DSR, Jeddah, Saudi Arabia. IFPIP:1080-830-1443
6 · The paper itself

Abstract

N6-methyladenosine (6 mA) is the most common internal modification in eukaryotic mRNA. Mass spectrometry and site-directed mutagenesis, two of the most common conventional approaches, have been shown to be laborious and challenging. In recent years, there has been a rising interest in analyzing RNA sequences to systematically investigate mutated locations. Using novel methods for feature development, the current work aimed to identify 6 mA locations in RNA sequences. Following the generation of these novel features, they were used to train an ensemble of models using methods such as stacking, boosting, and bagging. The trained ensemble models were assessed using an independent test set and k-fold cross validation. When compared to baseline predictors, the suggested model performed better and showed improved ratings across the board for key measures of accuracy.

Indexed as

AdenosineRNAResearch DesignRNA, MessengerAdenosineRNARNA, Messenger

Identifiers

PMID38589431
PMCPMC11001897

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.