Evidence map›Paper›PMID 38589235›Full record

ArticleBMJ case reports2024

Denosumab and sclerotherapy for recurrent spinal aneurysmal bone cyst in a child.

Raj Singh, Sreekumar Madasswery, Matt Colman, Paul McKeegan Kent

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raj SinghCollege of Medicine, Rush University Medical Center, Chicago, Illinois, USA.ORCID http://orcid.org/0000-0003-1764-2344
Sreekumar MadassweryRush University Rush Medical College, Chicago, Illinois, USA.
Matt ColmanRush University Rush Medical College, Chicago, Illinois, USA.
Paul McKeegan KentMedical Director, FibroFighters Foundation LLC, Temecula, California, USA paulkentmd@fibrofighters.org.
Rush University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aneurysmal bone cyst (ABC) is a non-malignant, locally destructive, blood-filled lesion in the bone that tends to grow aggressively. A young girl presented with a rapid recurrence after aggressive surgery of a large symptomatic sacral-spinal ABC. After a multidisciplinary tumour board, she was successfully treated with sclerotherapy and monthly intravenous denosumab. The patient has maintained asymptomatic for over 36 months now and has returned to full activity and strength. She never required surgery and has had radiologic resolution of the lesions. Treatment of recurrent ABC requires a multidisciplinary team approach. We believe this to be the first report to use this combined therapy to provide an alternative to morbid surgery for children with ABCs.

Indexed as

Bone Cysts, AneurysmalDenosumabAdministration, IntravenousChildFemaleHumansSacrumSclerotherapyDenosumabCalcium and boneChemotherapyOrthopaedicsPaediatric oncologyPaediatrics (drugs and medicines)

Identifiers

PMID38589235
PMCPMC11015305
OpenAlexW4394581451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.