Evidence map›Paper›PMID 38589201›Full record

ReviewArchives of disease in childhood2024

Children born to subfertile couples, how are they doing? Evidence from research.

Nadine Iman Schottler, Alastair G Sutcliffe

Abstract readReview
In one paragraph

Review in Archives of disease in childhood, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nadine Iman SchottlerPopulation, Policy and Practice Unit, University College London, London, UK.
Alastair G SutcliffeInstitute of Child Health, University College London, London, UK a.sutcliffe@ucl.ac.uk.ORCID 0000-0001-8542-6155

Funding

A US-UK Collaborative Study of the Health of Children Born From In Vitro Fertilization: From Conception Through Young AdulthoodR01HD112081 · NICHD · EMORY UNIVERSITY · PI BARBARA JOAN LUKE, Philip Lupo · 2023 to 2026
$2.3M
Integrating Epidemiologic and Genomic Data to Elucidate the Genetic Overlap Between Congenital Anomalies and Pediatric CancerR01CA284531 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Chad Daniel Huff, Philip Lupo · 2023 to 2026
$1.9M
NCI NIH HHS R01 CA284531NICHD NIH HHS R01 HD112081Wellcome Trust
6 · The paper itself

Abstract

More than 10 million children have been born with assisted reproductive technology (ART) as we begin to enter the third generation of individuals conceived by ART. Here we summarise key messages from an enlarging body of literature regarding their health. Earlier research had pointed towards increases in perinatal, neonatal and neurological risks, such as preterm birth, low birth weight, congenital malformations and cerebral palsy. Many of these risks have continued to persist in most recent work but have shown reduction. Newer research proposes long-term cardiometabolic and endocrine concerns. Fortunately, most reports conclude there is little or no risk of increased childhood malignancy or abnormal neurodevelopment. Moving forward, new research may benefit from changes in comparator groups and a better understanding of infertility per se in ART, and the confounding role it probably plays in many of the known risk associations, to reliably scan the horizon for health threats for individuals born after ART.

Indexed as

InfertilityReproductive Techniques, AssistedChildCongenital AbnormalitiesFemaleHumansInfant, NewbornMalePregnancyRisk FactorsAdolescent HealthChild HealthEpidemiologyGrowthInfant Development

Identifiers

PMID38589201
PMCPMC11458832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.