Evidence map›Paper›PMID 38588564›Full record

SynthesisThe British journal of radiology2025

Safety and efficacy of cryoablation of soft-tissue tumours: a systematic review.

Sylvain Bodard, Clement Marcelin, Adrian Kastler, Platon M Dimopoulos, Elena N Petre, Julien Frandon, Leo Razakamanantsoa, Francois H Cornelis

Abstract readSystematic Review
In one paragraph

Synthesis in The British journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Percutaneous Management of Desmoid Tumors.Current oncology reports · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Image-guided cryoablation for uterine diseases: a systematic review.Quantitative imaging in medicine and surgery · 2025
    Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sylvain BodardDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0001-5381-3361
Clement MarcelinDepartment of Radiology, Centre Hospitalo-Universitaire de Bordeaux, Bordeaux 33076, France.
Adrian KastlerNeuroradiology and MRI Unit, Grenoble Alpes University Hospital, Grenoble Cedex 09, France.
Platon M DimopoulosDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Elena N PetreDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Julien FrandonRadiology Department, Nimes University Hospital, Nimes 30900, France.
Leo RazakamanantsoaDepartment of Interventional Radiology and Oncology, Tenon Hospital, Sorbonne University, Paris 75020, France.
Francois H CornelisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0002-1058-0884

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCINCI NIH HHS P30 CA008748NIH
6 · The paper itself

Abstract

objectivesTo assess the safety and efficacy of percutaneous cryoablation (CA) of soft-tissue tumours [desmoid tumours (DTs), vascular malformations (VMs), and abdominal wall endometriosis (AWE)].

methodsThis systematic review of studies published before January 2024 encompassed a detailed analysis of CA techniques and technical aspects for the treatment of soft-tissue tumours. Data concerning CA efficacy, complication rates, and other relevant metrics were extracted and included for analysis.

resultsThe analysis included 27 studies totalling 554 CA procedures. For DT (13 studies, 393 sessions), CA showed an average pain reduction of 79 ± 17% (range: 57-100) and a lesion volume decrease of 71.5 ± 9.8% (range: 44-97). VM (4 studies, 58 sessions) had a 100% technical success rate and an average pain reduction of 72 ± 25% (range: 63-85). The average pain reduction for AWE (6 studies, 103 sessions) was 82 ± 13% (range: 62-100). Overall, the complication rate for CA was low, with minor adverse events (AEs) in about 20% of patients and major events in less than 5% of patients.

conclusionsShowing substantial efficacy in pain reduction and lesion volume decrease, as well as low incidence of severe AE, CA presents as a highly effective and safe alternative for the treatment of soft-tissue tumours. ADVANCES IN KNOWLEDGE: CA is effective and safe in treating soft-tissue tumours, particularly DT, VM, and AWE.

Indexed as

CryosurgeryEndometriosisSoft Tissue NeoplasmsFemaleHumansTreatment Outcomeabdominal wall endometriosiscryoablationdesmoid tumoursystematic reviewvascular malformation

Identifiers

PMID38588564
PMCPMC12089779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.