Evidence map›Paper›PMID 38587593›Full record

ReviewJournal of microbiology (Seoul, Korea)2024

The Microbiome Matters: Its Impact on Cancer Development and Therapeutic Responses.

In-Young Chung, Jihyun Kim, Ara Koh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of microbiology (Seoul, Korea), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Microbiota in cancer: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

In-Young Chung *Department of Life Sciences, Pohang University of Science and Technology, Pohang, 37673, Republic of Korea. iychung@postech.ac.kr.
Jihyun Kim *Department of Life Sciences, Pohang University of Science and Technology, Pohang, 37673, Republic of Korea.
Ara KohDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, 37673, Republic of Korea. ara.koh@postech.ac.kr.ORCID http://orcid.org/0000-0001-7673-034X

Funding

Korean Fund for Regenerative Medicine (KFRM) KFRM 22A0301L1National Research Foundation of Korea (NRF) 2021R1I1A1A01052756National Research Foundation of Korea (NRF) 2023R1A2C1002876the Basic Science Institute 2021R1A6C101A390
6 · The paper itself

Abstract

In the evolving landscape of cancer research, the human microbiome emerges as a pivotal determinant reshaping our understanding of tumorigenesis and therapeutic responses. Advanced sequencing technologies have uncovered a vibrant microbial community not confined to the gut but thriving within tumor tissues. Comprising bacteria, viruses, and fungi, this diverse microbiota displays distinct signatures across various cancers, with most research primarily focusing on bacteria. The correlations between specific microbial taxa within different cancer types underscore their pivotal roles in driving tumorigenesis and influencing therapeutic responses, particularly in chemotherapy and immunotherapy. This review amalgamates recent discoveries, emphasizing the translocation of the oral microbiome to the gut as a potential marker for microbiome dysbiosis across diverse cancer types and delves into potential mechanisms contributing to cancer promotion. Furthermore, it highlights the adverse effects of the microbiome on cancer development while exploring its potential in fortifying strategies for cancer prevention and treatment.

Indexed as

DysbiosisGastrointestinal MicrobiomeNeoplasmsBacteriaCarcinogenesisHumansImmunotherapyMicrobiotaMouthCancerChemotherapyImmunotherapyMicrobiomeOral microbiome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.