Evidence map›Paper›PMID 38587544›Full record

ArticleWiener klinische Wochenschrift2024

Impact of age on the transmission of SARS-CoV-2 in healthcare workers : Influence of nonoccupational risk factors.

Luis Corral-Gudino, María Piedad Del-Amo-Merino, Jésica Abadía-Otero, Irene Merino-Velasco, Yolanda Lorenzo-Fernández, Jesús García-Cruces-Méndez, José María Eiros-Bouza, Marta Domínguez-Gil González

Abstract read
In one paragraph

Article in Wiener klinische Wochenschrift, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clinical Symptom Patterns as Predictors of SARS-CoV-2 Infection in Healthcare Workers in Puerto Rico.International journal of environmental research and public health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luis Corral-GudinoDepartment of Internal Medicine, Dermatology and Toxicology. Hospital Universitario Rio Hortega, Valladolid. School of Medicine, Universidad de Valladolid, Avda. Ramón y Cajal, 7, 47005, Valladolid, Spain. luis.corral@uva.es.ORCID http://orcid.org/0000-0003-0151-5420
María Piedad Del-Amo-MerinoOccupational Risk Prevention Service, Hospital Universitario Río Hortega, Gerencia Regional de Salud de Castilla y Leon (SACYL), C/Dulzaina n°2, 47012, Valladolid, Spain.ORCID http://orcid.org/0000-0003-2024-9156
Jésica Abadía-OteroDepartment of Internal Medicine, Hospital Universitario Río Hortega, Gerencia Regional de Salud de Castilla y Leon (SACYL), C/Dulzaina n°2, 47012, Valladolid, Spain.ORCID http://orcid.org/0000-0001-9629-6229
Irene Merino-VelascoDepartment of Microbiology, Hospital Universitario Río Hortega Universidad de Valladolid, Gerencia Regional de Salud de Castilla y Leon (SACYL), C/Dulzaina n°2, 47012, Valladolid, Spain.ORCID http://orcid.org/0000-0001-5841-7392
Yolanda Lorenzo-FernándezOccupational Risk Prevention Service, Hospital Universitario Río Hortega, Gerencia Regional de Salud de Castilla y Leon (SACYL), C/Dulzaina n°2, 47012, Valladolid, Spain.ORCID http://orcid.org/0000-0002-6620-4634
Jesús García-Cruces-MéndezDepartment of Preventive Medicine and Hospital Epidemiology, Hospital Universitario Río Hortega, Gerencia Regional de Salud de Castilla y Leon (SACYL), C/Dulzaina n°2, 47012, Valladolid, Spain.ORCID http://orcid.org/0000-0003-2113-8722
José María Eiros-BouzaDepartment of Microbiology, Hospital Universitario Rio Hortega, Valladolid. School of Medicine, Universidad de Valladolid, Avda. Ramón y Cajal, 7, 47005, Valladolid, Spain.ORCID http://orcid.org/0000-0002-5357-6340
Marta Domínguez-Gil GonzálezDepartment of Microbiology, Hospital Universitario Río Hortega Universidad de Valladolid, Gerencia Regional de Salud de Castilla y Leon (SACYL), C/Dulzaina n°2, 47012, Valladolid, Spain.ORCID http://orcid.org/0000-0001-7957-5656

Funding

Sociedad Castellano-Leonesa y Cántabra de Medicina Interna (SOCALMI). 2023
6 · The paper itself

Abstract

backgroundThe incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV‑2) infection was highest among older adults early in the COVID-19 pandemic; however, this pattern was later reversed with young adults showing the highest incidence. The aim of this study was to identify risk factors in healthcare workers (HCWs) associated with this evolution.

methodsWe conducted a survey nested within a prospective cohort study of 680 HCWs from a tertiary referral public hospital who received 2 doses of SARS-CoV‑2 vaccine in January and February 2021 (VACCICO-VAO cohort). In October 2022 all participants were invited to participate in a survey. Risk factors were tested for association with COVID-19 ever, the number of COVID-19 episodes, and the time to the first episode.

resultsAmong 350 respondents (51% response rate, 90% female, mean age 48.1 years), 323 COVID-19 episodes were diagnosed during the study period. Multivariable analysis revealed that age < 35 years vs. > 50 years (odds ratio, OR 2.12, 95% confidence interval, CI 1.27-3.51; P = 0.004) and not maintaining social distance at social events (OR: 1.82, 95% CI: 1.16-3.19; P = 0.011) were associated with a higher risk of COVID-19. Age < 35 years (hazard ratio, HR 1.70, 95% CI 1.14-2.54; P = 0.010), and not maintaining social distance (HR 1.34, 95% CI 1.05-1.72; P = 0.020) were also associated with the time to the first episode.

conclusionsThe youngest HCWs had the highest incidence rate of COVID-19, which was not explained by occupational risk factors or health conditions. The increase in nonoccupational exposure since the end of the lockdowns in summer 2020 could by a key factor.

Indexed as

COVID-19Health PersonnelAdultAge FactorsAustriaCohort StudiesCOVID-19 VaccinesFemaleHumansIncidenceInfectious Disease Transmission, Patient-to-ProfessionalMaleMiddle AgedPandemicsProspective StudiesRisk FactorsCOVID-19 VaccinesCOVID-19Health personnelSocial distanceVaccinationYoung people

Identifiers

PMID38587544
PMCPMC11327202

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.