ArticleSmall (Weinheim an der Bergstrasse, Germany)2024
SPOOC (Sensor for Periodic Observation of Choline): An Integrated Lab-on-a-Spoon Platform for At-Home Quantification of Choline in Infant Formula.
Article in Small (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Self-Powered Microfluidic Device with Laser-Converted Graphene Electrodes for Immobilization-Free Electrochemical Detection of MPOX Virus DNA via Mismatch-Driven Nanocomplexes.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Machine learning-assisted paper-based chemiluminescence biosensor for choline quantification in infant milk: toward portable nutritional quality monitoring.Scientific reports · 2026Article
- Device for Electrochemical Caffeine Analysis in Fluids (DECAF): A Stir-Bar-Embedded Sensor for Real-Time Caffeine Analysis in Commercial and Homemade Beverages.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Safer breastfeeding with a wearable sensor for monitoring maternal acetaminophen transfer through breast milk.Device · 2025Article
- Bilisense: An affordable sensor for on-site diagnosis of jaundice and prevention of kernicterus.Biosensors & bioelectronics · 2025Article
- Mom and Baby Wellness with a Smart Lactation Pad: A Wearable Sensor-Embedded Lactation Pad for on-Body Quantification of Glucose in Breast Milk.Advanced functional materials · 2025Article
- A Point-of-Care Device for Theophylline Quantification in Human Milk Using Laser-Induced Graphene Electrodes.ACS applied nano materials · 2025Article
- Benchtop Fabrication and Integration of Laser-Induced Graphene Strain Gauges and Stimulation Electrodes in Muscle on a Chip Devices.Advanced functional materials · 2025Article
- Lab-on-a-lollipop (LoL) platform for preventing food-induced toxicity: all-in-one system for saliva sampling and electrochemical detection of vanillin.Lab on a chip · 2024Article
- Flexible Acetylcholine Neural Probe with a Hydrophobic Laser-Induced Graphene Electrode and a Fluorous-Phase Sensing Membrane.ACS materials letters · 2024Article
- Towards sustainable and humane dairy farming: A low-cost electrochemical sensor for on-site diagnosis of milk fever.Biosensors & bioelectronics · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Choline is an essential micronutrient for infants' brain development and health. To ensure that infants receive the needed daily dose of choline, the U.S. Food and Drug Administration (FDA) has set requirements for choline levels in commercialized infant formulas. Unfortunately, not all families can access well-regulated formulas, leading to potential inadequacies in choline intake. Economic constraints or difficulties in obtaining formulas, exacerbated by situations like COVID-19, prompt families to stretch formulas. Accurate measurement of choline in infant formulas becomes imperative to guarantee that infants receive the necessary nutritional support. Yet, accessible tools for this purpose are lacking. An innovative integrated sensor for the periodic observation of choline (SPOOC) designed for at-home quantification of choline in infants' formulas and milk powders is reported. This system is composed of a choline potentiometric sensor and ionic-liquid reference electrode developed on laser-induced graphene (LIG) and integrated into a spoon-like device. SPOOC includes a micro-potentiometer that conducts the measurements and transmits results wirelessly to parents' mobile devices. SPOOC demonstrated rapid and accurate assessment of choline levels directly in pre-consuming infant formulas without any sample treatment. This work empowers parents with a user-friendly tool for choline monitoring promoting informed nutritional decision-making in the care of infants.
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Registered trials
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