ArticleJournal of the American Heart Association2024
Trends and Disparities in Valvular Heart Disease Mortality in the United States From 1999 to 2020.
Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Expanding indications for transcatheter aortic valve implantation: time for valve-in-valve in mechanical prosthesis? A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Pooled it
- Temporal Trends in Hospitalization and Interventions for Aortic Stenosis in Canada, 2012-2024.CJC open · 2026Article
- Valve-in-Valve TAVR Versus Redo Surgery in Women With Degenerated Aortic Bioprosthesis: A Single-Center Experience.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- Chronic kidney disease related mortality trends with and without valvular heart disease among adults in the United States: A retrospective analysis.BMC cardiovascular disorders · 2026Article
- A case of artificial intelligence-enhanced diagnostics leading to heart transplantation.Nature medicine · 2026Article
- Comparing Direct TAVR to Balloon Aortic Valvuloplasty-TAVR in Patients with Cardiogenic Shock and Severe Aortic Stenosis-A TriNetX-Based Study.Journal of clinical medicine · 2026Article
- Racial trends in outcomes and access to treatment for mitral regurgitation: a South London population cohort study.Open heart · 2026Observational
- Rebuilding life after heart valve surgery: The VALCAR(E)_QoL study on rehabilitation and quality of life.MethodsX · 2026Article
- Early rehospitalisation after transcatheter aortic valve implantation: incidence, predictors and impact on mortality.Open heart · 2026Article
- Valvular Heart Disease Mortality in the United States, 2023.JACC. Advances · 2026Article
- The Emerging Role of Artificial Intelligence in the Assessment of Valvular Heart Disease with Cardiac Imaging.Current cardiology reports · 2026Review
- Assessment of limited cardiac ultrasound to screen for mitral regurgitation.Echo research and practice · 2025Article
- Concurrent aortic stenosis and hypertension: mortality trends in US older adults from 1999-2020.Future cardiology · 2025Article
- Current Status of Cardiovascular Disease in Asian Americans: One Size Does Not Fit All.Current cardiology reports · 2025Review
- Article
- Left ventricular rigor mortis interferes with postmortem aortic root geometry.International journal of legal medicine · 2025Article
- Age Differences in Aortic Stenosis.Reviews in cardiovascular medicine · 2025Review
- Aortic Valve Replacement in the Current Era.Journal of clinical medicine · 2025Review
- Trends in complications of cardiac and vascular prosthetic devices, implants, and grafts mortality rate in the United States (1999-2020).Annals of medicine and surgery (2012) · 2025Review
- Trends, gender, and racial disparities in patients with mortality due to paroxysmal tachycardia: A nationwide analysis from 1999-2020.PloS one · 2025Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPercutaneous heart valve procedures have been increasingly performed over the past decade, yet real-world mortality data on valvular heart disease (VHD) in the United States remain limited. METHODS AND
resultsWe queried the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research database among patients ≥15 years old from 1999 to 2020. VHD and its subtypes were listed as the underlying cause of death. We calculated age-adjusted mortality rate (AAMR) per 100 000 individuals and determined overall trends by estimating the average annual percent change using the Joinpoint regression program. Subgroup analyses were performed based on demographic and geographic factors. In the 22-year study, there were 446 096 VHD deaths, accounting for 0.80% of all-cause mortality (56 014 102 people) and 2.38% of the total cardiovascular mortality (18 759 451 people). Aortic stenosis recorded the highest mortality of VHD-related death in both male (109 529, 61.74%) and female (166 930, 62.13%) populations. The AAMR of VHD has declined from 8.4 (95% CI, 8.2-8.5) to 6.6 (95% CI, 6.5-6.7) per 100 000 population. Similar decreasing AAMR trends were also seen for the VHD subtypes. Men recorded higher AAMR for aortic stenosis and aortic regurgitation, whereas women had higher AAMR for mitral stenosis and mitral regurgitation. Mitral regurgitation had the highest change in average annual percent change in AAMR.
conclusionsThe mortality rate of VHD among the US population has declined over the past 2 decades. This highlights the likely efficacy of increasing surveillance and advancement in the management of VHD, resulting in improved outcomes.
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