Evidence map›Paper›PMID 38586905›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2024

Clinical Utility of Tectal Plate Measurements on Magnetic Resonance Imaging in Progressive Supranuclear Palsy.

Abigail Amrami, Neha Atulkumar Singh, Farwa Ali, Nha Trang Thu Pham, Yehkyoung C Stephens, Keith A Josephs, Jennifer L Whitwell

Open access · bronzeAbstract read
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Abigail AmramiDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Neha Atulkumar SinghDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-3614-9179
Farwa AliDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Nha Trang Thu PhamDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Yehkyoung C StephensDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Keith A JosephsDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-2930-8634
Jennifer L WhitwellDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0001-6914-1563
Mayo Clinic · US

Funding

Longitudinal Multi-modal Imaging in Progressive Supranuclear Palsy SyndromesR01NS089757 · NINDS · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A, WHITWELL, JENNIFER LOUISE · 2015 to 2024
$5.6M
NINDS NIH HHS R01 NS089757
6 · The paper itself

Abstract

backgroundMidbrain atrophy is a characteristic feature of progressive supranuclear palsy (PSP), observed in PSP-Richardson's syndrome (PSP-RS) and to a lesser extent PSP-parkinsonism (PSP-P).

objectiveOur aim was to critically evaluate the utility of manual magnetic resonance imaging measurements of the midbrain tectal plate as a diagnostic biomarker in PSP.

methodsLength of the tectal plate and width of the superior and inferior colliculi were measured in 40 PSP (20 PSP-RS and 20 PSP-P) patients and compared with 20 Parkinson's disease and 20 healthy control subjects.

resultsTectal plate length was reduced in both PSP groups compared with Parkinson's disease and control subjects and was most abnormal in PSP-RS followed by PSP-P. Reduced tectal plate length was associated with worse PSP Rating Scale scores.

conclusionsSimple manual measurements of tectal plate length show utility as a diagnostic biomarker in PSP, particularly for PSP-RS.

Indexed as

Magnetic Resonance ImagingSupranuclear Palsy, ProgressiveAgedFemaleHumansMaleMiddle AgedParkinson DiseaseTectum Mesencephalimidbrain atrophyprogressive supranuclear palsytectal plate

Identifiers

PMID38586905
PMCPMC11341258
OpenAlexW4394576021

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.