Evidence map›Paper›PMID 38586179›Full record

ArticleResuscitation plus2024

Non-linear association between the time required to reaching temperature targets and the neurological outcome in patients undergoing targeted temperature management after out-of-hospital cardiac arrest: Observational multicentre cohort study.

Tetsuro Nishimura, Toshihiro Hatakeyama, Hisako Yoshida, Satoshi Yoshimura, Takeyuki Kiguchi, Taro Irisawa, Tomoki Yamada, Kazuhisa Yoshiya, Changhwi Park, Takuya Ishibe and 20 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Resuscitation plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Tetsuro NishimuraDepartment of Traumatology and Critical Care Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan.
Toshihiro HatakeyamaDepartment of Emergency and Critical Care Medicine, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minami-Koshigaya, Koshigaya, Saitama 343-8555, Japan.
Hisako YoshidaDepartment of Medical Statistics, Osaka Metropolitan University, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan.
Satoshi YoshimuraDepartment of Preventive Services, School of Public Health, Graduate School of Medicine, Kyoto University, Yoshida-Konoemachi, Sakyo-ku, Kyoto 606-8501, Japan.
Takeyuki KiguchiDepartment of Critical Care and Trauma Center, Osaka General Medical Center, 3-1-56 Bandai-Higashi, Sumiyoshi-ku, Osaka 558-8558, Japan.
Taro IrisawaDepartment of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Tomoki YamadaEmergency and Critical Care Medical Center, Osaka Police Hospital, 10-31, Kitayamacho, Tennoji-ku, Osaka 543-0035, Japan.
Kazuhisa YoshiyaDepartment of Emergency and Critical Care Medicine, Kansai Medical University General Medical Center, 10-15 Fumizono-cho, Moriguchi, Osaka 570-8507, Japan.
Changhwi ParkDepartment of Emergency Medicine, Tane General Hospital, 1-12-21, Kujyominami, Nishi-ku, Osaka 550-0025, Japan.
Takuya IshibeDepartment of Emergency and Critical Care Medicine, Kindai University Faculty of Medicine, 377-2, Ohnohigashi, Osaka-Sayama, Osaka 589-8511, Japan.
Yoshiki YagiOsaka Mishima Emergency and Critical Care Center, 11-1, Minamiakutagawa-cho, Takatsuki, Osaka 569-1124, Japan.
Masafumi KishimotoOsaka Prefectural Nakakawachi Emergency and Critical Care Center, 3-4-13, Nishiiwata, Higashiosaka, Osaka 578-0947, Japan.
Sung-Ho KimSenshu Trauma and Critical Care Center, 2-23, Rinkuoraikita, Izumisano, Osaka 598-8577, Japan.
Yasuyuki HayashiSenri Critical Care Medical Center, Saiseikaisenri Hospital, 1-1-6, Tsukumodai, Suita, Osaka 565-0862, Japan.
Yusuke ItoSenri Critical Care Medical Center, Saiseikaisenri Hospital, 1-1-6, Tsukumodai, Suita, Osaka 565-0862, Japan.
Taku SogabeTraumatology and Critical Care Medical Center, National Hospital Organization Osaka National Hospital, 1-1-6, Tsukumodai, Suita, Osaka 565-0862, Japan.
Takaya MorookaEmergency and Critical Care Medical Center, Osaka City General Hospital, 2-13-22, Miyakojima-hondori, Miyakojima-ku, Osaka 534-0021, Japan.
Haruko SakamotoDepartment of Pediatrics, Osaka Red Cross Hospital, 5-30 Fudegasakicho, Tennoji-ku, Osaka 543-8555, Japan.
Keitaro SuzukiEmergency and Critical Care Medical Center, Kishiwada Tokushukai Hospital, 4-27-1 Kamoricho, Kishiwada, Osaka 596-8522, Japan.
Fumiko NakamuraDepartment of Emergency and Critical Care Medicine, Kansai Medical University General Medical Center, 10-15 Fumizono-cho, Moriguchi, Osaka 570-8507, Japan.
Tasuku MatsuyamaDepartment of Emergency Medicine, Kyoto Prefectural University of Medicine, Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Yohei OkadaDepartment of Preventive Services, School of Public Health, Graduate School of Medicine, Kyoto University, Yoshida-Konoemachi, Sakyo-ku, Kyoto 606-8501, Japan.
Norihiro NishiokaDepartment of Preventive Services, School of Public Health, Graduate School of Medicine, Kyoto University, Yoshida-Konoemachi, Sakyo-ku, Kyoto 606-8501, Japan.
Satoshi MatsuiDivision of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Shunsuke KimataDepartment of Preventive Services, School of Public Health, Graduate School of Medicine, Kyoto University, Yoshida-Konoemachi, Sakyo-ku, Kyoto 606-8501, Japan.
Shunsuke KawaiDepartment of Preventive Services, School of Public Health, Graduate School of Medicine, Kyoto University, Yoshida-Konoemachi, Sakyo-ku, Kyoto 606-8501, Japan.
Yuto MakinoDepartment of Preventive Services, School of Public Health, Graduate School of Medicine, Kyoto University, Yoshida-Konoemachi, Sakyo-ku, Kyoto 606-8501, Japan.
Tetsuhisa KitamuraDivision of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Taku IwamiDepartment of Preventive Services, School of Public Health, Graduate School of Medicine, Kyoto University, Yoshida-Konoemachi, Sakyo-ku, Kyoto 606-8501, Japan.
Yasumitsu MizobataDepartment of Traumatology and Critical Care Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We evaluated associations between outcomes and time to achieving temperature targets during targeted temperature management of out-of-hospital cardiac arrest. Methods: Using Comprehensive Registry of Intensive Care for out-of-hospital cardiac arrest Survival (CRITICAL) study, we enrolled all patients transported to participating hospitals from 1 July 2012 through 31 December 2017 aged ≥ 18 years with out-of-hospital cardiac arrest of cardiac aetiology and who received targeted temperature management in Osaka, Japan. Primary outcome was Cerebral Performance Category scale of 1 or 2 one month after cardiac arrest, designated as "one-month favourable neurological outcome". Non-linear multivariable logistic regression analyses assessed the primary outcome based on time to reaching temperature targets. In patients subdivided into quintiles based on time to achieving temperature targets, multivariable logistic regression calculated adjusted odds ratios and 95% confidence intervals. Results: We analysed 473 patients. In non-linear multivariable logistic regression analysis, Conclusion: Non-linear multivariable logistic regression analysis could clearly describe the association between neurological outcome in patients with out-of-hospital cardiac arrest and the time from the introduction of targeted temperature management to reaching the temperature targets.

Indexed as

Cardiac arrestCardiopulmonary resuscitationEmergency medical servicesEmergency medicineResuscitationTargeted temperature management

Identifiers

PMID38586179
PMCPMC10995978

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.