ArticlebioRxiv : the preprint server for biology2024
Faster inference of complex demographic models from large allele frequency spectra.
Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We present momi3, a new method for inferring complex demographic models using genetic variation data sampled from many populations. momi3 features many improvements over its predecessor momi2 (Kamm, Terhorst, Durbin, et al., 2020), including support for continuous migration, just-in-time compilation, and execution on GPUs; a standardized interface for specifying demographic models; and a novel importance sampling strategy that enables it to efficiently analyze data from a large number of samples. Together, these improvements lead to speedups of as much as 1000× over existing state-of-the-art methods such as
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