Evidence map›Paper›PMID 38585983›Full record

ArticlebioRxiv : the preprint server for biology2024

Mutational scanning of

James L Shepherdson, David M Granas, Jie Li, Zara Shariff, Stephen P Plassmeyer, Alex S Holehouse, Michael A White, Barak A Cohen

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

James L ShepherdsonDepartment of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-3288-7000
David M GranasDepartment of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Jie LiDepartment of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Zara ShariffDepartment of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Stephen P PlassmeyerDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-8986-0650
Alex S HolehouseDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-4155-5729
Michael A WhiteDepartment of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0001-8511-6026
Barak A CohenDepartment of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-3350-2715
Washington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
PROMOTERSR01GM092910 · NIGMS · WASHINGTON UNIVERSITY · PI Barak A Cohen · 2011 to 2026
$6.6M
Uncovering the regulatory logic of gene expression encoded by disordered regionsDP2CA290639 · NCI · WASHINGTON UNIVERSITY · PI Alex S Holehouse · 2023 to 2026
$2.3M
Cell-Based Assays For Deep Mutational Scans of Transcription FactorsR21HG012146 · NHGRI · WASHINGTON UNIVERSITY · PI COHEN, BARAK A · 2021 to 2021
$433k
Multiplex functional assay of variant effect in the retinal transcription factor CRXF30EY033640 · NEI · WASHINGTON UNIVERSITY · PI SHEPHERDSON, JAMES LEWIS · 2022 to 2025
$178k
NCI NIH HHS DP2 CA290639NCI NIH HHS P30 CA091842NEI NIH HHS F30 EY033640NHGRI NIH HHS R21 HG012146NIGMS NIH HHS R01 GM092910
6 · The paper itself

Abstract

Cone-Rod Homeobox, encoded by

Indexed as

acidic exposure modelCRXdeep mutational scanintrinsically disordered domainretinaretinopathytranscription factor

Identifiers

PMID38585983
PMCPMC10996540
OpenAlexW4393216871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.