Evidence map›Paper›PMID 38585982›Full record

ArticlebioRxiv : the preprint server for biology2024

Sir2 and Fun30 regulate ribosomal DNA replication timing via MCM helicase positioning and nucleosome occupancy.

Carmina Lichauco, Eric J Foss, Tonibelle Gatbonton-Schwager, Nelson F Athow, Brandon Lofts, Robin Acob, Erin Taylor, James J Marquez, Uyen Lao, Shawna Miles and 1 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Carmina LichaucoTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
Eric J FossTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.ORCID 0000-0002-5553-9412
Tonibelle Gatbonton-SchwagerTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
Nelson F AthowTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
Brandon LoftsTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
Robin AcobTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
Erin TaylorTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
James J MarquezTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
Uyen LaoTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
Shawna MilesTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
Antonio BedalovTranslational Science and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.ORCID 0000-0002-7373-8255
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZA

Funding

Origin firing at repetitive sequences and genome replication - Admin SupplementR01GM117446 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BEDALOV, ANTONIO · 2016 to 2023
$4.3M
NIGMS NIH HHS R01 GM117446
6 · The paper itself

Abstract

The association between late replication timing and low transcription rates in eukaryotic heterochromatin is well-known, yet the specific mechanisms underlying this link remain uncertain. In

Identifiers

PMID38585982
PMCPMC10996493
OpenAlexW4393231425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.