Evidence map›Paper›PMID 38585980›Full record

ArticlebioRxiv : the preprint server for biology2025

2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons.

Jingcheng Shi, Boaz Nutkovich, Dahlia Kushinsky, Bovey Y Rao, Stephanie A Herrlinger, Emmanouil Tsivourakis, Tiberiu S Mihaila, Margaret E Conde Paredes, Katayun Cohen-Kashi Malina, Cliodhna K O'Toole and 6 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Jingcheng ShiDepartment of Neuroscience, Columbia University, New York, NY, United States.
Boaz NutkovichDepartment of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.
Dahlia KushinskyDepartment of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.
Bovey Y RaoDepartment of Neuroscience, Columbia University, New York, NY, United States.
Stephanie A HerrlingerDepartment of Neuroscience, Columbia University, New York, NY, United States.
Emmanouil TsivourakisStavros Niarchos Foundation Center for Precision Psychiatry and Mental Health, New York, NY, United States.
Tiberiu S MihailaDepartment of Neuroscience, Columbia University, New York, NY, United States.
Margaret E Conde ParedesDepartment of Neuroscience, Columbia University, New York, NY, United States.
Katayun Cohen-Kashi MalinaDepartment of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.
Cliodhna K O'TooleDepartment of Neuroscience, Columbia University, New York, NY, United States.
Hyun Choong YongDepartment of Neuroscience, Columbia University, New York, NY, United States.
Brynn M SannerDepartment of Neuroscience, Columbia University, New York, NY, United States.
Angel XieDepartment of Neuroscience, Columbia University, New York, NY, United States.
Erdem VarolTandon School of Engineering, New York University, New York, NY, United States.
Attila LosonczyDepartment of Neuroscience, Columbia University, New York, NY, United States.ORCID 0000-0002-7064-0252
Ivo SpiegelDepartment of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.
Columbia University · USWeizmann Institute of Science · ILNew York University · USStavros Niarchos Foundation · GR

Funding

Medical Scientist Training ProgramT32GM145440 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STEVEN L REINER · 2022 to 2026
$7.3M
Optimization, application and dissemination of high-speed hybrid multiphoton volumetric imaging technologiesU01NS115530 · NINDS · ROCKEFELLER UNIVERSITY · PI LOSONCZY, ATTILA, VAZIRI, ALIPASHA · 2020 to 2023
$4.7M
Microcircuit, cellular and molecular dissection of impaired hippocampal function in a mouse model of the 22q11.2 deletionR01MH124047 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOGOS, JOSEPH A, LOSONCZY, ATTILA · 2020 to 2024
$3.8M
Experimental and modeling investigations into microcircuit, cellular and subcellular determinants of hippocampal ensemble recruitment to contextual representationsR01MH124867 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOSONCZY, ATTILA, POIRAZI, PANAYIOTA · 2021 to 2025
$3.4M
Control of Axon Initial Segment in EpilepsyR01NS121106 · NINDS · STANFORD UNIVERSITY · PI LOSONCZY, ATTILA, SOLTESZ, IVAN · 2021 to 2025
$3.4M
Local Circuit Control of Rapid Plasticity and Tunable Ensemble Formation in the HippocampusRF1NS133381 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOSONCZY, ATTILA, SOLTESZ, IVAN · 2023 to 2023
$2.6M
Dissecting the role of the dentate gyrus microcircuit to improve cognitive discrimination in aging and Alzheimer's DiseaseRF1AG080818 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FUSI, STEFANO, HEN, RENE · 2023 to 2023
$2.5M
Activity-dependent endocannabinoid control in epilepsyR01NS131728 · NINDS · STANFORD UNIVERSITY · PI Attila Losonczy, IVAN SOLTESZ · 2023 to 2026
$2.3M
Local Circuit Control of Rapid Plasticity and Tunable Ensemble Formation in the HippocampusR01NS133381 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI Attila Losonczy, IVAN SOLTESZ · 2026 to 2026
$752k
Transcriptional basis of stereotyped neural architecturesR00MH128772 · NIMH · NEW YORK UNIVERSITY · PI Erdem Varol · 2024 to 2026
$734k
NIA NIH HHS RF1 AG080818NIGMS NIH HHS T32 GM145440NIMH NIH HHS R00 MH128772NIMH NIH HHS R01 MH124047NIMH NIH HHS R01 MH124867NINDS NIH HHS R01 NS121106NINDS NIH HHS R01 NS131728NINDS NIH HHS R01 NS133381NINDS NIH HHS RF1 NS133381NINDS NIH HHS U01 NS115530
6 · The paper itself

Abstract

Neural circuits are characterized by genetically and functionally diverse cell types. A mechanistic understanding of circuit function is predicated on linking the genetic and physiological properties of individual neurons. However, it remains highly challenging to map the molecular properties onto functionally heterogeneous neuronal subtypes in mammalian cortical circuits

Identifiers

PMID38585980
PMCPMC10996538
OpenAlexW4393180801

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.