ArticlebioRxiv : the preprint server for biology2024
Traumatic injury causes selective degeneration and TDP-43 mislocalization in human iPSC-derived
Eric J Martin, Citlally Santacruz, Angela Mitevska, Ian E Jones, Gopinath Krishnan, Fen-Biao Gao, John D Finan, Evangelos Kiskinis
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 7 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors at 3 institutions in 1 country.
Eric J MartinThe Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Citlally SantacruzDepartment of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL, USA.
Angela MitevskaDepartment of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL, USA.ORCID 0000-0003-2401-8806 Ian E JonesDepartment of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL, USA.
Gopinath KrishnanRNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Fen-Biao GaoRNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.
John D FinanDepartment of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL, USA.
Evangelos KiskinisThe Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0001-8342-8616 University of Illinois Chicago · USNorthwestern University · USUniversity of Massachusetts Chan Medical School · US
Funding
Investigating Pathogenic Mechanisms of Frontotemporal Dementia Caused by Mutations in CHMP2B and TBK1R37NS057553 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GAO, FEN-BIAO · 2018 to 2024
$4.3MNovel tools for in vitro electrophysiology and neurotrauma modelingR01NS113935 · NINDS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FINAN, JOHN D · 2020 to 2024
$3.0MInvestigating the Contribution of ALS/FTD-Associated Mutations in the NEK1 Kinase to Disease PathophysiologyR01NS134166 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Evangelos Kiskinis, Udai B Pandey · 2023 to 2026
$3.0MDetermining How Defective Nucleo-Cytoplasmic Trafficking Leads To Neurodegeneration In C9orf72-Related ALS And FTDR01NS104219 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KISKINIS, EVANGELOS · 2018 to 2022
$2.3MUnderstanding Frontotemporal Dementia Using Drosophila and iPSC ModelsRF1NS101986 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GAO, FEN-BIAO · 2022 to 2022
$2.1MNINDS NIH HHS R01 NS104219NINDS NIH HHS R01 NS113935NINDS NIH HHS R01 NS134166NINDS NIH HHS R37 NS057553NINDS NIH HHS RF1 NS101986
6 · The paper itselfAbstract
A hexanucleotide repeat expansion (HRE) in
Indexed as
amyotrophic lateral sclerosis (ALS)C9orf72frontotemporal dementia (FTD)iPSC modelsmotor neuronsNeurotraumaTDP-43traumatic brain injury (TBI)
Identifiers
PMID38585915
PMCPMC10996466
OpenAlexW4393181156
What OpenQuestion holds
Textmetadata
LicenceCC BY
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